Drugs and manners of administration that meet the 30 month clock (for an originator removal calculation) for the 2019 April Cycle

Page last updated: 12 October 2018

This page lists those drugs and manners of administration (MoA) that will have a weighted average disclosed price calculation performed for the 2019 April Cycle and whether or not the drug/MoA meets the 30 month clock for an originator removal calculation for the 2019 April Cycle.

In general, originator removal calculations will apply to price disclosure data submitted for the data collection period commencing 1 April 2018 when a drug has been on F2 for at least 2.5 years (30 months), with:

  • calculations for originator removal being at least 3 years (36 months) after the drug has been on F2; and
  • the reduction day for originator removed calculations being at least 3.5 years (42 months) after movement to F2.

Once a drug/MoA has met the 30 month clock it will have an originator removal calculation performed in each price disclosure cycle thereafter.

Some exceptions to this timing and removal of originator brand data can be found on the 2015 Price Disclosure Changes – Fact Sheet.

Further information on determination of originator brands, the removal of originator brand data from the weighted average disclosure price calculation and the 30 month clock is available on the 2015 Price Disclosure Changes – Fact Sheet.

Drug/MoAs that have not met the 30 month clock may satisfy the criteria for a future cycle. These will be published before the end of the data submission period in each subsequent cycle.

Drugs and manners of administration that meet the 30 month clock for originator removal calculation for the 2019 April Cycle

*means that no originator brand has been determined and therefore the 30 month clock (for an originator removal calculation) will not be applied.

Legal Instrument Drug

Legal Instrument MoA

30 month clock met for the 2019 April Cycle

Abacavir with lamivudine

Oral

No

Abatacept

Injection

No

Acarbose

Oral

No

Aciclovir

Application to the eye

Yes

Aciclovir

Oral

Yes

Acitretin

Oral

Yes

Adefovir

Oral

Yes

Alendronic acid

Oral

Yes*

Alendronic acid with colecalciferol

Oral

Yes

Alendronic acid with colecalciferol and calcium

Oral

Yes

Allopurinol

Oral

Yes

Alprazolam

Oral

Yes*

Amiodarone

Oral

Yes

Amisulpride

Oral

Yes

Amitriptyline

Oral

Yes*

Amlodipine

Oral

Yes

Amlodipine with atorvastatin

Oral

Yes

Amlodipine with valsartan

Oral

Yes

Amlodipine with valsartan and hydrochlorothiazide

Oral

Yes

Amoxicillin

Oral

Yes

Amoxicillin with clavulanic acid

Oral

Yes

Ampicillin

Injection

Yes*

Anastrozole

Oral

Yes

Apomorphine

Injection

No

Aripiprazole

Injection

No

Aripiprazole

Oral

No

Aspirin

Oral

Yes*

Atenolol

Oral

Yes

Atomoxetine

Oral

No

Atorvastatin

Oral

Yes

Azacitidine

Injection

No

Azathioprine

Oral

Yes

Azithromycin

Oral

Yes

Baclofen

Injection

No

Baclofen

Oral

Yes

Betamethasone

Application

Yes

Betamethasone

Injection

No

Betaxolol

Application to the eye

Yes

Bicalutamide

Oral

Yes

Bimatoprost

Application to the eye

No

Bisacodyl

Oral

Yes*

Bisacodyl

Rectal

Yes*

Bisoprolol

Oral

Yes

Bivalirudin

Injection

No

Bleomycin

Injection

Yes*

Bosentan

Oral

No

Brimonidine

Application to the eye

Yes

Brinzolamide

Application to the eye

Yes

Bromocriptine

Oral

Yes

Budesonide with formoterol

Inhalation by Mouth

No

Bupropion

Oral

Yes

Cabergoline

Oral

Yes

Calcipotriol with betamethasone

Application

No

Calcitriol

Oral

Yes

Candesartan

Oral

Yes

Candesartan with hydrochlorothiazide

Oral

Yes

Capecitabine

Oral

Yes

Captopril

Oral

Yes

Carbamazepine

Oral

Yes

Carbomer

Application to the eye

Yes

Carboplatin

Injection

Yes*

Carvedilol

Oral

Yes

Cefaclor

Oral

Yes

Cefalexin

Oral

Yes

Cefalotin

Injection

Yes*

Cefazolin

Injection

Yes*

Cefepime

Injection

Yes*

Cefotaxime

Injection

Yes*

Ceftriaxone

Injection

Yes*

Cefuroxime

Oral

No

Celecoxib

Oral

Yes

Certolizumab pegol

Injection

No

Chorionic gonadotrophin

Injection

No

Ciclosporin

Oral

Yes

Cimetidine

Oral

No

Ciprofloxacin

Application to the eye

Yes

Ciprofloxacin

Oral

Yes

Cisplatin

Injection

Yes*

Citalopram

Oral

Yes

Clarithromycin

Oral

Yes

Clindamycin

Oral

Yes

Clomifene

Oral

Yes

Clomipramine

Oral

Yes

Clonazepam

Oral

Yes

Clonidine

Oral

No

Clopidogrel

Oral

Yes

Clopidogrel with aspirin

Oral

Yes

Clozapine

Oral

Yes

Codeine with paracetamol

Oral

Yes

Colchicine

Oral

Yes

Cromoglycic acid

Inhalation by mouth

No

Cyproterone

Oral

Yes

Desferrioxamine

Injection

Yes*

Desvenlafaxine

Oral

Yes

Dexamethasone

Application to the eye

No

Dexamethasone

Injection

Yes

Dexamethasone

Oral

No

Dexamethasone with framycetin and gramicidin

Application to the ear

Yes

Diazepam

Oral

Yes

Diclofenac

Oral

Yes

Dicloxacillin

Oral

No

Digoxin

Oral

Yes

Diltiazem

Oral

Yes

Diphenoxylate with atropine

Oral

Yes

Dipyridamole with Aspirin

Oral

Yes

Docetaxel

Injection

Yes*

Donepezil

Oral

Yes

Dorzolamide

Application to the eye

Yes

Dorzolamide with timolol

Application to the eye

Yes

Dosulepin

Oral

No

Doxorubicin

Injection/intravesical

Yes*

Doxorubicin - pegylated liposomal

Injection

Yes

Doxycycline

Oral

Yes*

Duloxetine

Oral

Yes

Dutasteride

Oral

No

Electrolyte replacement, oral

Oral

Yes*

Enalapril

Oral

Yes

Enalapril with hydrochlorothiazide

Oral

Yes

Entecavir

Oral

No

Epirubicin

Injection/intravesical

Yes*

Eplerenone

Oral

No

Epoprostenol

Injection

No

Eprosartan

Oral

No

Erythromycin

Oral

Yes*

Escitalopram

Oral

Yes

Esomeprazole

Oral

Yes

Esomeprazole and clarithromycin and amoxicillin

Oral

No

Estradiol

Oral

No

Estradiol

Transdermal

No

Estradiol

Vaginal

No

Etanercept

Injection

No

Etoposide

Injection

No

Etoposide

Oral

No

Exemestane

Oral

Yes

Famciclovir

Oral

Yes

Famotidine

Oral

Yes*

Felodipine

Oral

Yes

Fentanyl

Buccal

No

Fentanyl

Sublingual

No

Fentanyl

Transdermal

Yes

Filgrastim

Injection

Yes

Flecainide

Oral

Yes

Flucloxacillin

Injection

Yes*

Flucloxacillin

Oral

Yes*

Fluconazole

Injection

Yes

Fluconazole

Oral

Yes

Fludarabine

Injection

Yes

Fludarabine

Oral

No

Fluorouracil

Injection

Yes*

Fluoxetine

Oral

Yes

Flutamide

Oral

No

Fluticasone

Inhalation by mouth

No

Fluticasone with salmeterol

Inhalation by mouth

No

Fluvastatin

Oral

Yes

Fluvoxamine

Oral

Yes

Folinic acid

Injection

Yes

Folinic acid

Oral

No

Follitropin alfa

Injection

No

Fosinopril

Oral

Yes*

Fosinopril with hydrochlorothiazide

Oral

Yes*

Furosemide

Injection

Yes

Furosemide

Oral

Yes

Gabapentin

Oral

Yes

Galantamine

Oral

Yes

Ganciclovir

Injection

No

Gemcitabine

Injection

Yes*

Gemfibrozil

Oral

Yes*

Gentamicin

Application to the eye

No

Gentamicin

Injection

Yes

Glibenclamide

Oral

Yes

Gliclazide

Oral

Yes

Glimepiride

Oral

Yes

Glipizide

Oral

Yes

Glyceryl trinitrate

Buccal/sublingual

Yes

Glyceryl trinitrate

Transdermal

No

Granisetron

Injection

Yes

Granisetron

Oral

No

Hydrochlorothiazide with amiloride

Oral

No

Hydrocortisone

Application

Yes

Hydrocortisone

Application to the eye

No

Hydrocortisone

Injection

No

Hydrocortisone

Oral

No

Hydrocortisone

Rectal

No

Hydroxocobalamin

Injection

Yes*

Hydroxychloroquine

Oral

Yes

Hyoscine

Injection

No

Hypromellose

Application to the eye

Yes*

Hypromellose with carbomer 980

Application to the eye

Yes

Hypromellose with dextran

Application to the eye

Yes

Ibuprofen

Oral

No

Idarubicin

Injection

Yes

Idarubicin

Oral

No

Imatinib

Oral

No

Imipramine

Oral

Yes

Imiquimod

Application

Yes

Indapamide

Oral

Yes

Indometacin

Oral

Yes

Infliximab

Injection

No

Interferon beta-1b

Injection

Yes

Ipratropium

Inhalation

Yes

Ipratropium

Inhalation by mouth

No

Irbesartan

Oral

Yes

Irbesartan with hydrochlorothiazide

Oral

Yes

Irinotecan

Injection

Yes*

Iron polymaltose complex

Injection

Yes*

Isosorbide dinitrate

Oral

Yes

Isosorbide mononitrate

Oral

Yes

Isotretinoin

Oral

Yes

Itraconazole

Oral

No

Ketoprofen

Oral

Yes

Labetalol

Oral

Yes

Lamivudine

Oral

Yes

Lamivudine with zidovudine

Oral

Yes

Lamotrigine

Oral

Yes

Lansoprazole

Oral

Yes

Latanoprost

Application to the eye

Yes

Latanoprost with timolol

Application to the eye

Yes

Leflunomide

Oral

Yes

Lercanidipine

Oral

Yes

Letrozole

Oral

Yes

Levetiracetam

Oral

Yes

Levodopa with carbidopa

Intra-intestinal

Yes

Levodopa with carbidopa

Oral

Yes

Levonorgestrel with ethinylestradiol

Oral

Yes

Levothyroxine

Oral

Yes

Lisinopril

Oral

Yes

Loperamide

Oral

Yes

Losartan

Oral

No

Macrogol 3350

Oral

Yes

Medroxyprogesterone

Injection

Yes

Medroxyprogesterone

Oral

Yes

Meloxicam

Oral

Yes

Memantine

Oral

Yes

Metformin

Oral

Yes

Methadone

Oral

Yes

Methotrexate

Injection

Yes*

Methotrexate

Oral

Yes*

Methyldopa

Oral

Yes

Methylphenidate

Oral

Yes

Methylprednisolone

Application

No

Methylprednisolone

Injection

Yes

Metoclopramide

Injection

No

Metoclopramide

Oral

Yes

Metoprolol

Oral

Yes

Metoprolol succinate

Oral

Yes

Metronidazole

Oral

Yes

Mianserin

Oral

Yes*

Minocycline

Oral

Yes

Mirtazapine

Oral

Yes*

Mitozantrone

Injection

Yes*

Moclobemide

Oral

Yes

Modafinil

Oral

No

Mometasone

Application

Yes

Montelukast

Oral

Yes

Morphine

Injection

Yes

Morphine

Oral

Yes

Mycophenolic acid

Oral

Yes

Naloxone

Injection

No

Naltrexone

Oral

Yes

Naproxen

Oral

Yes

Nevirapine

Oral

Yes

Nicorandil

Oral

Yes

Nifedipine

Oral

Yes

Nitrazepam

Oral

Yes

Nizatidine

Oral

Yes

Norethisterone

Oral

Yes

Norethisterone with ethinylestradiol

Oral

Yes

Norfloxacin

Oral

Yes*

Nortriptyline

Oral

No

Octreotide

Injection

Yes

Olanzapine

Injection

No

Olanzapine

Oral

Yes

Olmesartan

Oral

No

Olmesartan with amlodipine

Oral

No

Olmesartan with hydrochlorothiazide

Oral

No

Omalizumab

Injection

No

Omeprazole

Oral

Yes

Ondansetron

Injection

Yes

Ondansetron

Oral

Yes

Oxaliplatin

Injection

Yes*

Oxazepam

Oral

Yes

Oxybutynin

Oral

Yes

Oxybutynin

Transdermal

No

Oxycodone

Oral

Yes

Oxycodone

Rectal

No

Paclitaxel

Injection

Yes*

Pamidronic acid

Injection

No

Pantoprazole

Oral

Yes

Paracetamol

Oral

Yes*

Paraffin

Application to the eye

Yes*

Paroxetine

Oral

Yes

Pegfilgrastim

Injection

No

Pemetrexed

Injection

No

Perindopril

Oral

Yes

Perindopril with amlodipine

Oral

Yes

Perindopril with indapamide

Oral

Yes

Phenoxymethylpenicillin

Oral

Yes*

Pilocarpine

Application to the eye

No

Pindolol

Oral

Yes*

Pioglitazone

Oral

Yes

Piroxicam

Oral

Yes

Polyvinyl alcohol

Application to the eye

Yes

Potassium chloride

Oral

Yes*

Potassium chloride with potassium bicarbonate

Oral

No

Pramipexole

Oral

Yes

Pravastatin

Oral

Yes

Prazosin

Oral

Yes

Prednisolone

Oral

Yes*

Prednisolone

Rectal

No

Prednisone

Oral

Yes*

Pregabalin

Oral

No

Prochlorperazine

Oral

Yes

Propranolol

Oral

Yes

Quetiapine

Oral

Yes

Quinapril

Oral

Yes

Quinine

Oral

No

Rabeprazole

Oral

Yes

Raloxifene

Oral

Yes

Ramipril

Oral

Yes

Ranitidine

Oral

Yes

Riluzole

Oral

Yes

Risedronic acid

Oral

Yes

Risedronic acid and calcium

Oral

Yes*

Risperidone

Injection

No

Risperidone

Oral

Yes

Rivastigmine

Oral

No

Rivastigmine

Transdermal

No

Rizatriptan

Oral

No

Rosuvastatin

Oral

Yes

Roxithromycin

Oral

Yes

Salbutamol

Inhalation

Yes

Salbutamol

Inhalation by mouth

Yes

Selegiline

Oral

Yes

Sertraline

Oral

Yes

Sildenafil

Oral

Yes

Simvastatin

Oral

Yes

Somatropin

Injection

No

Sorbitol with sodium citrate dihydrate and sodium lauryl sulfoacetate

Rectal

Yes*

Sotalol

Oral

Yes

Spironolactone

Oral

Yes

Sucralfate

Oral

Yes

Sulfasalazine

Oral

Yes

Sumatriptan

Nasal

No

Sumatriptan

Oral

Yes

Tacrolimus

Oral

Yes

Tamoxifen

Oral

Yes

Telmisartan

Oral

Yes

Telmisartan with amlodipine

Oral

Yes

Telmisartan with hydrochlorothiazide

Oral

Yes

Temazepam

Oral

Yes

Temozolomide

Oral

Yes

Tenofovir

Oral

No

Tenofovir with emtricitabine

Oral

No

Terbinafine

Oral

Yes

Timolol

Application to the eye

Yes

Tinidazole

Oral

Yes

Tirofiban

Injection

Yes

Tobramycin

Application to the eye

No

Tobramycin

Inhalation

No

Tobramycin

Inhalation by mouth

No

Tobramycin

Injection

No

Topiramate

Oral

Yes

Topotecan

Injection

Yes

Tramadol

Injection

Yes

Tramadol

Oral

Yes

Trandolapril

Oral

Yes

Tranexamic acid

Oral

No

Triamcinolone

Application

Yes

Triamcinolone

Injection

No

Triamcinolone with neomycin, gramicidin and nystatin

Application to the ear

Yes

Trimethoprim

Oral

Yes

Trimethoprim with sulfamethoxazole

Oral

Yes

Tropisetron

Injection

No

Ursodeoxycholic acid

Oral

Yes

Valaciclovir

Oral

Yes

Valganciclovir

Oral

No

Valproic acid

Oral

Yes

Valsartan

Oral

Yes

Valsartan with hydrochlorothiazide

Oral

Yes

Vancomycin

Injection

Yes

Vancomycin

Oral

No

Venlafaxine

Oral

Yes

Verapamil

Oral

Yes

Vincristine

Injection

No

Vinorelbine

Injection

Yes

Vinorelbine

Oral

No

Voriconazole

Oral

No

Ziprasidone

Oral

Yes

Zoledronic acid

Injection

No

Zolmitriptan

Oral

Yes

Zonisamide

Oral

No