First New Brand Price Reductions

Page last updated: 1 February 2023

In accordance with Division 3A of Part VII of the National Health Act 1953 a first new brand statutory price reduction (FNB SPR) will apply when the first new brand (new brand) of a pharmaceutical item (trigger item) that is bioequivalent or biosimilar and has the same manner of administration (MoA) as an existing pharmaceutical item (existing item) is listed on the Pharmaceutical Benefits Scheme (PBS). 

The criteria for a FNB SPR applies irrespective of the formulary status of the drug. When the FNB is listed for a drug that is in F1, the drug becomes multi-branded and moves from F1 to the F2 formulary. Some older drugs in F2 may also meet the criteria for a FNB SPR.

Application of FNB SPRs

Refer to the First New Brand Statutory Price Reduction Policy (PDF 381KB) - (Word 351KB) for details about the application of a FNB SPR, such as what percentage reduction will apply, including where the existing brand has an effective price, how the reductions are flowed-on to combination items and related brands, how to apply to list a first new brand on the PBS and obligations for first new brands such as guarantee of supply.

Ministerial Discretion

The Minister for Health can exercise discretion to not apply, or to reduce the magnitude of, an FNB SPR. For more information on the types of information and the matters that might be considered relevant to the exercise of Ministerial Discretion in relation to FNB SPR and the timeframes for making such an application, refer to the Ministerial Discretion web page.

History of FNB SPR reforms

As part of the PBS reforms in 2007, the 12.5% FNB price reduction policy that had operated as an administrative policy since 1 August 2005, was legislated. Through further reforms, the FNB SPR increased from 12.5% to 16% on 1 February 2011, then again from 16% to up to 25% on 1 October 2018.

From 1 July 2022, the National Health Amendment (Enhancing the Pharmaceutical Benefits Scheme) Act 2021 gives effect to the reforms in the Strategic Agreement with Medicines Australia and the Generic and Biosimilar Medicines Association. Amongst other things, the amendments to SPRs ensure that FNB SPRs automatically apply to existing pharmaceutical items, so new price agreements under section 85AD of the Act will not be required.

Historical FNB reductions

The below lists include the drugs and MoAs that have been subject to a statutory or administrative FNB reduction. The Department endeavours to update this list each time a new FNB SPR takes effect. New drugs and MoAs subject to a FNB SPR since the last update are in bold italics

1. Statutory 12.5%, 16% and 25% Reductions

1. Statutory 12.5%, 16% and 25% Reductions

Drug
(for combination drug – 16% or up to 25% applied to component)

Manner of Administration

Date of Effect
for 16% or up to 25% SPR

Abacavir with lamivudine

Oral

1 February 2018

Abacavir with Lamivudine (Applied to the lamivudine component)

Oral

1 August 2012

Abacavir with Lamivudine and Zidovudine (Applied to the lamivudine component)

Oral

1 August 2012

Abatacept

Injection

1 April 2017

Acamprosate

Oral

1 June 2018

Acarbose

Oral

1 June 2016

Aciclovir

Application to the eye

1 August 2021

Acitretin

Oral

1 April 2014

Adalimumab

Injection

1 April 2021

Adefovir

Oral

1 December 2014

Adrenaline

Injection

1 June 2018

Alendronic Acid

Oral

1 December 2007

Ambrisentan

Oral

1 December 2020

Amisulpride

Oral

1 August 2007

Amlodipine

Oral

1 August 2007

Amlodipine with Atorvastatin (amlodipine component)*
(atorvastatin component)**

Oral

1 August 2007*
1 April 2012**

Amlodipine with Valsartan

Oral

1 December 2012

Amlodipine with Valsartan and hydrochlorothiazide

Oral

1 December 2012

Anastrozole

Oral

1 April 2012

Apomorphine

Injection

1 February 2016

Aripiprazole

Oral

1 December 2016

Arsenic 

Injection

1 December 2020

Aspirin

Oral

1 August 2012

Atazanavir

Oral

1 April 2019

Atazanavir with cobicistat (Applied to the atazanavir component)

Oral

1 April 2019

Atenolol

Oral

1 April 2011

Atomoxetine

Oral

1 August 2016

Atorvastatin

Oral

1 April 2012

Azacitidine

Injection

1 June 2016

Azithromycin

Oral

1 August 2009

Baclofen

Injection

1 April 2016

Bevacizumab

Injection

1 June 2021

Bicalutamide

Oral

1 August 2008

Bimatoprost

Application to the eye

1 October 2017

Bisoprolol

Oral

1 August 2009

Bivalirudin

Injection

1 December 2016

Bleomycin

Injection

1 April 2012

Bortezomib

Injection

1 June 2021

Bosentan

Oral

1 August 2017

Budesonide with eformoterol

Inhalation by mouth

1 April 2018

Buprenorphine

Transdermal

1 June 2018

Cabazitaxel

Injection

1 April 2021

Cabergoline

Oral

1 August 2009

Calcipotriol with betamethasone

Application

1 February 2017

Candesartan

Oral

1 April 2013

Candesartan with Hydrochlorothiazide (Applied to Candesartan component)

Oral

1 April 2013

Candesartan with Hydrochlorothiazide (Applied to Hydrochlorothiazide component)

Oral

1 August 2013

Capecitabine

Oral

1 August 2014

Carbimazole

Oral

1 February 2023

Carbomer

Application to the eye

1 April 2014

Carvedilol

Oral

1 April 2008

Cefepime

Injection

1 December 2010

Celecoxib

Oral

1 December 2014

Cephalothin/Cefalotin

Injection

1 August 2008

Cephazolin

Injection

1 December 2010

Certolizumab pegol

Injection

1 April 2018

Chorionic gonadotrophin

Injection

1 August 2017

Cinacalcet

Oral

1 April 2021

Clindamycin

Oral

1 December 2014

Clonidine

Oral

1 April 2017

Clopidogrel

Oral

1 April 2010

Clopidogrel with Aspirin

Oral

1 April 2010

Colchicine

Oral

1 August 2021

Cyproterone

Oral

1 August 2012

Darunavir

Oral

1 October 2021

Dasatinib

Oral

1 December 2021

Deferasirox

Oral

1 August 2021

Desvenlafaxine

Oral

1 April 2015

Dexamethasone

Injection

1 December 2011

Diazepam

Oral

1 August 2008

Dicloxacillin

Oral

1 June 2018

Diltiazem

Oral

1 August 2007

Dimethyl fumarate

Oral

1 February 2022

Dipyridamole with aspirin

Oral

1 December 2014

Domperidone

Oral

1 February 2023

Donepezil

Oral

1 April 2013

Dorzolamide

Application to the eye

1 April 2015

Dorzolamide with timolol

Application to the eye

1 December 2014

Doxorubicin - Pegylated Liposomal

Injection

1 April 2014

Duloxetine

Oral

1 April 2013

Dutasteride

Oral

1 December 2017

Dutasteride with tamsulosin

Oral

1 June 2020

Enalapril Maleate with Hydrochlorothiazide

Oral

1 April 2008

Enoxaparin

Injection

1 June 2018

Entecavir

Oral

1 December 2016

Epirubicin

Injection/Intravesical

1 April 2011

Eplerenone

Oral

1 June 2016

Epoprostenol

Injection

1 August 2014

Eprosartan

Oral

1 April 2013

Eprosartan with Hydrochlorothiazide (Applied to Eprosartan component)

Oral

1 April 2013

Erlotinib

Oral

1 April 2021

Etanercept

Injection

1 April 2017

Everolimus

Oral

1 June 2018

Exemestane

Oral

1 August 2011

Ezetimibe

Oral

1 June 2018

Ezetimibe and Rosuvastatin

Oral

1 June 2018

Ezetimibe with Simvastatin

Oral

1 June 2018

Felodipine

Oral

1 August 2007

Fenofibrate

Oral

1 June 2019

Fentanyl

Transdermal

1 August 2011

Filgrastim

Injection

1 April 2011

Fingolimod

Oral

1 December 2022

Flecainide

Oral

1 October 2016

Fluconazole

Injection

1 December 2007

Fludarabine

Injection

1 December 2008

Fludrocortisone

Oral

1 February 2022

Fluticasone

Inhalation by mouth

1 June 2017

Fluticasone with Salmeterol

Inhalation by mouth

1 June 2017

Follitropin Alfa

Injection

1 August 2016

Fosinopril with Hydrochlorothiazide

Oral

1 August 2007

Frusemide

Oral

1 April 2012

Fulvestrant

Injection

1 December 2021

Galantamine

Oral

1 August 2010

Ganciclovir

Injection

1 April 2018

Ganirelix

Injection

1 April 2021

Gefitinib

Oral

1 October 2020

Gemcitabine

Injection

1 April 2009

Gemfibrozil

Oral

1 April 2008

Glatiramer

Injection

1 February 2022

Glucose

Injection

1 August 2009

Hydromorphone

Injection

1 August 2019

Hydroxocobalamin

Injection

1 December 2010

Hydroxycarbamide

Oral

1 October 2020

Hydroxychloroquine

Oral

1 August 2012

Hyoscine

Injection

1 December 2017

Icatibant

Injection

1 October 2020

Ibuprofen

Oral

1 October 2017

Idarubicin

Injection

1 April 2011

Imatinib

Oral

1 October 2016

Imiquimod

Application

1 December 2012

Indapamide

Oral

1 August 2012

Infliximab

Injection

1 December 2015

Insulin glargine

Injection

1 October 2019

Interferon Beta-1b

Injection

1 April 2013

Irbesartan

Oral

1 April 2013

Irbesartan with Hydrochlorothiazide

Oral

1 April 2013

Isotretinoin

Oral

1 April 2011

Itraconazole

Oral

1 December 2016

Ivabradine

Oral

1 October 2018

Lacosamide

Oral

1 April 2022

Lamivudine

Oral

1 August 2012

Lamivudine with Zidovudine (Applied to the lamivudine component)

Oral

1 August 2012

Lamivudine with Zidovudine (Applied to the zidovudine component)

Oral

1 August 2013

Latanoprost

Application to the eye

1 August 2012

Latanoprost with Timolol

Application to the eye

1 August 2012

Leflunomide

Oral

1 August 2011

Lenalidomide

Oral

1 February 2023

Lercanidipine

Oral

1 August 2007

Letrozole

Oral

1 April 2012

Levodopa with carbidopa

Oral

1 April 2020

Levodopa with carbidopa and entacapone

Oral

1 August 2020

Levonorgestrel with Ethinylestradiol

Oral

1 April 2013

Levothyroxine

Oral

1 February 2022

Lincomycin

Injection

1 June 2018

Loperamide

Oral

1 December 2012

Losartan

Oral

1 April 2013

Lurasidone

Oral

1 August 2020

Macrogol 3350

Oral

1 December 2010

Mefenamic acid

Oral

1 February 2022

Meloxicam

Oral

1 August 2007

Memantine

Oral

1 April 2010

Mercaptopurine

Oral

1 December 2020

Mesalazine

Oral

1 February 2022

Methenamine

Oral

1 February 2021

Methylprednisolone

Injection

1 August 2011

Metoclopramide

Oral

1 April 2014

Metoprolol succinate

Oral

1 August 2014

Metronidazole

Injection

1 April 2008

Misoprostol

Oral

1 August 2013

Modafinil

Oral

1 April 2016

Mometasone

Application

1 April 2013

Montelukast

Oral

1 August 2013

Morphine

Injection

1 August 2016

Morphine

Oral

1 August 2009

Moxonidine

Oral

1 June 2018

Mycophenolic Acid

Oral

1 April 2012

Naloxone

Injection

1 April 2017

Naltrexone

Oral

1 December 2007

Nebivolol

Oral

1 August 2018

Nevirapine

Oral

1 December 2012

Nicorandil

Oral

1 April 2015

Nifedipine

Oral

1 August 2007

Nitrofurantoin

Oral

1 August 2020

Nortriptyline

Oral

1 August 2017

Octreotide

Injection

1 December 2007

Olanzapine

Oral

1 April 2012

Olmesartan

Oral

1 April 2013

Olmesartan with Hydrochlorothiazide
(Applied to Olmesartan component)*
(Applied to the the Hydrochlorothiazide component)**

Oral

1 April 2013*
1 December 2016**

Olmesartan with Amlodipine (Applied to Olmersartan component )

Oral

1 April 2013

Olmesartan with Amlodipine and Hydrochlorothiazide

Oral

1 April 2020

Omalizumab

Injection

1 August 2014

Omeprazole and Clarithromycin and Amoxycillin

Oral

1 December 2010

Oxazepam

Oral

1 August 2010

Oxybutynin

Oral

1 August 2007

Oxycodone

Oral

1 December 2014

Palonosetron  

Injection

1 April 2022

Pegfilgrastim

Injection

1 April 2017

Perindopril with Indapamide

Oral

1 August 2007

Pioglitazone

Oral

1 April 2011

Plerixafor

Injection

1 October 2022

Polyethylene glycol 400 with proylene glycol

Application to the eye

1 February 2023

Pomalidomide

Oral

1 October 2022

Posaconazole 

Oral

1 December 2020

Pramipexole

Oral

1 August 2012

Prazosin

Oral

1 April 2012

Pregabalin

Oral

1 August 2017

Prochlorperazine

Oral

1 August 2010

Propranolol

Oral

1 August 2015

Quetiapine

Oral

1 April 2012

Rasagiline

Oral

1 Feb 2019

Raloxifene

Oral

1 December 2014

Riluzole

Oral

1 December 2012

Risedronate Sodium

Oral

1 April 2011

Risedronate Sodium and Calcium Carbonate

Oral

1 April 2011

Risedronate Sodium and Calcium Carbonate with Colecalciferol

Oral

1 April 2011

Risperidone

Oral

1 December 2008

Rituximab

Injection

1 October 2019

Rivastigmine

Transdermal

1 December 2016

Rizatriptan

Oral

1 December 2015

Rosuvastatin

Oral

1 April 2012

Salbutamol

Inhalation

1 April 2008

Salbutamol  

Inhalation by mouth

1 August 2011

Sevelamer

Oral

1 December 2019

Sildenafil

Oral

1 August 2014

Sitagliptin

Oral

1 August 2022

Sitagliptin with metformin

Oral

1 August 2022

Sodium Chloride

Injection

1 August 2009

Sodium Lactate Compound

Injection

1 August 2009

Somatropin

Injection

1 December 2015

Sorbitol with Sodium Citrate and Sodium Lauryl Sulfoacetate

Rectal

1 August 2010

Spironolactone

Oral

1 February 2021

Sunitinib

Oral

1 October 2021

Tacrolimus

Oral

1 December 2010

Tadalafil

Oral

1 October 2020

Telmisartan

Oral

1 April 2013

Telmisartan with Amlodipine (Applied to Telmarsartan component)

Oral

1 April 2013

Telmisartan with Hydrochlorothiazide (Applied to Telmisartan component)

Oral

1 April 2013

Telmisartan with Hydrochlorothiazide (Applied to hydrochlorothiazide component)

Oral

1 August 2013

Temazepam

Oral

1 August 2009

Temozolomide

Oral

1 December 2011

Tenofovir

Oral

1 August 2017

Tenofovir with emtricitabine

Oral

1 August 2017

Tenofovir with emtricitabine and efavirenz

Oral

1 August 2019

Teriflunomide

Oral

1 June 2019

Teriparatide

Injection

1 October 2021

Tetrabenazine

Oral

1 February 2023

Tiotropium

Inhalation by mouth

1 February 2020

Tirofiban

Injection

1 August 2014

Tobramycin

Injection

1 August 2016

Tocilizumab

Injection

1 December 2018

Topotecan

Injection

1 August 2012

Tranexamic acid

Oral

1 May 2017

Trastuzumab

Injection

1 August 2019

Ursodeoxycholic acid

Oral

1 April 2015

Valganciclovir

Oral

1 August 2017

Valproic Acid

Oral

1 August 2007

Valsartan

Oral

1 April 2013

Valsartan with Hydrochlorothiazide (Valsartan component)*
(Hydrochlorothiazide component)**

Oral

 1 April 2013*
1 December 2014**

Vancomycin

Injection

1 December 2007

Vancomycin

Oral

1 February 2023

Venlafaxine

Oral

1 April 2012

Voriconazole

Oral

1 February 2016

Ziprasidone

Oral

1 December 2013

Zoledronic Acid

Injection

1 December 2015

Zonisamide

Oral

1 June 2017

2. Administrative 12.5% reductions

2. Administrative 12.5% reductions

Drug

Manner of Administration

Date of Effect

Aciclovir

Oral

1 August 2006

Amitriptyline

Oral

1 August 2006

Amoxycillin

Oral

1 August 2006

Amoxycillin with Clavulanic Acid

Oral

1 August 2006

Bisacodyl

Oral

1 December 2005

Bupropion

Oral

1 April 2006

Calcitriol

Oral

1 August 2005

Calcium Folinate

Injection

1 April 2006

Captopril

Oral

1 August 2006

Carboplatin

Injection

1 December 2006

Cefaclor

Oral

1 August 2006

Cefotaxime

Injection

1 December 2006

Ceftriaxone

Injection

1 December 2006

Cefuroxime

Oral

1 August 2006

Cephalexin

Oral

1 August 2006

Cimetidine

Oral

1 August 2006

Ciprofloxacin

Oral

1 April 2006

Cisplatin

Injection

1 August 2006

Citalopram

Oral

1 August 2005

Clarithromycin

Oral

1 December 2005

Codeine with Paracetamol

Oral

1 August 2005

Cromoglycic Acid

Application to the eye

1 August 2006

Dexamphetamine

Oral

1 December 2005

Docetaxel

Injection

1 August 2005

Dolasetron

Injection

1 April 2006

Dolasetron

Oral

1 April 2006

Doxorubicin

Injection/Intravesical

1 August 2005

Electrolyte Replacement (Oral)

Oral

1 December 2005

Enalapril

Oral

1 August 2006

Erythromycin

Oral

1 December 2005

Escitalopram

Oral

1 August 2005

Esomeprazole

Oral

1 April 2006

Etidronic Acid and Calcium

Oral

1 August 2005

Etoposide

Injection

1 December 2005

Famciclovir

Oral

1 August 2006

Famotidine

Oral

1 August 2006

Fluconazole

Oral

1 December 2006

Fluorouracil

Injection

1 August 2006

Fluoxetine

Oral

1 August 2005

Fluvastatin

Oral

1 August 2005

Fluvoxamine

Oral

1 August 2005

Fosinopril

Oral

1 August 2006

Frusemide

Injection

1 December 2005

Gabapentin

Oral

1 August 2005

Gliclazide

Oral

1 April 2006

Glimepiride

Oral

1 April 2006

Granisetron

Oral

1 April 2006

Granisetron

Injection

1 April 2006

Imipramine

Oral

1 August 2006

Ipratropium

Inhalation

1 August 2005

Irinotecan

Injection

1 December 2006

Lansoprazole

Oral

1 April 2006

Lamotrigine

Oral

1 August 2005

Levetiracetam

Oral

1 August 2005

Lisinopril

Oral

1 August 2006

Metformin

Oral

1 December 2005

Methotrexate

Injection

1 December 2005

Methylphenidate

Oral

1 December 2005

Mirtazapine

Oral

1 August 2005

Mitozantrone

Injection

1 April 2006

Moclobemide

Oral

1 August 2005

Naratriptan

Oral

1 April 2007

Nizatidine

Oral

1 August 2006

Omeprazole

Oral

1 April 2006

Ondansetron

Injection

1 April 2006

Ondansetron

Oral

1 April 2006

Oxaliplatin

Injection

1 December 2006

Oxcarbazepine

Oral

1 August 2005

Paclitaxel

Injection

1 August 2005

Pantoprazole

Oral

1 April 2006

Paracetamol

Oral

1 December 2005

Paroxetine

Oral

1 August 2005

Pemetrexed

Injection

1 August 2005

Perindopril

Oral

1 August 2006

Pravastatin

Oral

1 August 2005

Quinapril

Oral

1 August 2006

Rabeprazole

Oral

1 April 2006

Ramipril

Oral

1 August 2006

Ranitidine

Oral

1 August 2006

Reboxetine

Oral

1 August 2005

Roxithromycin

Oral

1 December 2005

Sertraline

Oral

1 August 2005

Simvastatin

Oral

1 August 2005

Sumatriptan

Oral

1 April 2007

Terbinafine

Oral

1 December 2005

Tiagabine

Oral

1 August 2005

Topiramate

Oral

1 August 2005

Tramadol

Injection

1 August 2005

Tramadol

Oral

1 August 2005

Trandolapril

Oral

1 August 2006

Tropisetron

Injection

1 April 2006

Tropisetron

Oral

1 April 2006

Valaciclovir

Oral

1 August 2006

Vigabatrin

Oral

1 August 2005

Vinorelbine

Injection

1 August 2005

Zolmitriptan

Oral

1 April 2007

3. Partial 12.5% reductions

3. Partial 12.5% reductions

Drug

Manner of Administration

Details of Partial Reduction

Date of Effect

Doxorubicin, Pegylated Liposomal

Injection

3.5% (to account for use in ovarian cancer and Kaposi’s sarcoma)

1 August 2005

Ezetimibe with Simvastatin

Oral

Applied to the simvastatin component

1 August 2005

Metformin with Glibenclamide

Oral

Applied to the metformin component

1 December 2005

Gemcitabine

Injection

6.1% to account for use in pancreatic and  bladder cancer

1 August 2005

Rosiglitazone with Metformin

Oral

Applied to the metformin component

1 December 2005

Quinapril with Hydrochlorothiazide

Oral

Applied to the quinapril component

1 August 2006

Trandolapril with Verapamil

Oral

Applied to the trandolapril component

1 August 2006

Alendronic Acid with Colecalciferol

Oral

Applied to alendronic acid component

1 December 2007

Goserelin Acetate and Bicalutamide

Implantation/Oral

Applied to bicalutamide component

1 August 2008