First New Brand Price Reductions
Page last updated: 1 December 2020
Drugs where 12.5%, 16% and 25% reductions applied legislatively, administratively and partially
In accordance with division 3A of Part VII of the National Health Act 1953 a statutory price reduction of 25% is applied to existing PBS-listed products when the first new brand or item that is bioequivalent or biosimilar and has the same manner of administration as an existing brand or item lists on the PBS. This reduction increased from 12.5% to 16% on 1 February 2011, then again from 16% to 25% on 1 October 2018.
Administrative price reductions are applied in particular circumstances, for example, where a lower price offer is made by a sponsor.
Note: Statutory price reductions only occur once and are not applied to drugs that have taken a 12.5%, 16% or 25% administrative price reduction.
Note: New drugs with price reductions are in bold italics.
- 1. Statutory 12.5%, 16% and 25% Reductions
- 2. Administrative 12.5% reductions
- 3. Partial 12.5% reductions
1. Statutory 12.5%, 16% and 25% Reductions
| Drug (for combination drug – 16% or up to 25% applied to component) |
Manner of Administration | Date of Effect for 16% or up to 25% SPR |
|---|---|---|
| Abacavir with lamivudine | Oral | 1 February 2018 |
| Abacavir with Lamivudine (Applied to the lamivudine component) | Oral | 1 August 2012 |
| Abacavir with Lamivudine and Zidovudine (Applied to the lamivudine component) | Oral | 1 August 2012 |
| Abatacept | Injection | 1 April 2017 |
| Acamprosate | Oral | 1 June 2018 |
| Acarbose | Oral | 1 June 2016 |
| Acitretin | Oral | 1 April 2014 |
| Adefovir | Oral | 1 December 2014 |
| Adrenaline | Injection | 1 June 2018 |
| Alendronic Acid | Oral | 1 December 2007 |
| Ambrisentan | Oral | 1 December 2020 |
| Amisulpride | Oral | 1 August 2007 |
| Amlodipine | Oral | 1 August 2007 |
| Amlodipine with Atorvastatin (amlodipine component)* (atorvastatin component)** |
Oral | 1 August 2007* 1 April 2012** |
| Amlodipine with Valsartan | Oral | 1 December 2012 |
| Amlodipine with Valsartan and hydrochlorothiazide | Oral | 1 December 2012 |
| Anastrozole | Oral | 1 April 2012 |
| Apomorphine | Injection | 1 February 2016 |
| Aripiprazole | Oral | 1 December 2016 |
| Arsenic | Injection | 1 December 2020 |
| Aspirin | Oral | 1 August 2012 |
| Atazanavir | Oral | 1 April 2019 |
| Atazanavir with cobicistat (Applied to the atazanavir component) | Oral | 1 April 2019 |
| Atenolol | Oral | 1 April 2011 |
| Atomoxetine | Oral | 1 August 2016 |
| Atorvastatin | Oral | 1 April 2012 |
| Azacitidine | Injection | 1 June 2016 |
| Azithromycin | Oral | 1 August 2009 |
| Baclofen | Injection | 1 April 2016 |
| Bicalutamide | Oral | 1 August 2008 |
| Bimatoprost | Application to the eye | 1 October 2017 |
| Bisoprolol | Oral | 1 August 2009 |
| Bivalirudin | Injection | 1 December 2016 |
| Bleomycin | Injection | 1 April 2012 |
| Bosentan | Oral | 1 August 2017 |
| Budesonide with eformoterol | Inhalation by mouth | 1 April 2018 |
| Buprenorphine | Transdermal | 1 June 2018 |
| Cabergoline | Oral | 1 August 2009 |
| Calcipotriol with betamethasone | Application | 1 February 2017 |
| Candesartan | Oral | 1 April 2013 |
| Candesartan with Hydrochlorothiazide (Applied to Candesartan component) | Oral | 1 April 2013 |
| Candesartan with Hydrochlorothiazide (Applied to Hydrochlorothiazide component) | Oral | 1 August 2013 |
| Capecitabine | Oral | 1 August 2014 |
| Carbomer | Application to the eye | 1 April 2014 |
| Carvedilol | Oral | 1 April 2008 |
| Cefepime | Injection | 1 December 2010 |
| Celecoxib | Oral | 1 December 2014 |
| Cephalothin/Cefalotin | Injection | 1 August 2008 |
| Cephazolin | Injection | 1 December 2010 |
| Certolizumab pegol | Injection | 1 April 2018 |
| Chorionic gonadotrophin | Injection | 1 August 2017 |
| Clindamycin | Oral | 1 December 2014 |
| Clonidine | Oral | 1 April 2017 |
| Clopidogrel | Oral | 1 April 2010 |
| Clopidogrel with Aspirin | Oral | 1 April 2010 |
| Cyproterone | Oral | 1 August 2012 |
| Desvenlafaxine | Oral | 1 April 2015 |
| Dexamethasone | Injection | 1 December 2011 |
| Diazepam | Oral | 1 August 2008 |
| Dicloxacillin | Oral | 1 June 2018 |
| Diltiazem | Oral | 1 August 2007 |
| Dipyridamole with aspirin | Oral | 1 December 2014 |
| Donepezil | Oral | 1 April 2013 |
| Dorzolamide | Application to the eye | 1 April 2015 |
| Dorzolamide with timolol | Application to the eye | 1 December 2014 |
| Doxorubicin - Pegylated Liposomal | Injection | 1 April 2014 |
| Duloxetine | Oral | 1 April 2013 |
| Dutasteride | Oral | 1 December 2017 |
| Dutasteride with tamsulosin | Oral | 1 June 2020 |
| Enalapril Maleate with Hydrochlorothiazide | Oral | 1 April 2008 |
| Enoxaparin | Injection | 1 June 2018 |
| Entecavir | Oral | 1 December 2016 |
| Epirubicin | Injection/Intravesical | 1 April 2011 |
| Eplerenone | Oral | 1 June 2016 |
| Epoprostenol | Injection | 1 August 2014 |
| Eprosartan | Oral | 1 April 2013 |
| Eprosartan with Hydrochlorothiazide (Applied to Eprosartan component) | Oral | 1 April 2013 |
| Etanercept | Injection | 1 April 2017 |
| Everolimus | Oral | 1 June 2018 |
| Exemestane | Oral | 1 August 2011 |
| Ezetimibe | Oral | 1 June 2018 |
| Ezetimibe and Rosuvastatin | Oral | 1 June 2018 |
| Ezetimibe with Simvastatin | Oral | 1 June 2018 |
| Felodipine | Oral | 1 August 2007 |
| Fenofibrate | Oral | 1 June 2019 |
| Fentanyl | Transdermal | 1 August 2011 |
| Filgrastim | Injection | 1 April 2011 |
| Flecainide | Oral | 1 October 2016 |
| Fluconazole | Injection | 1 December 2007 |
| Fludarabine | Injection | 1 December 2008 |
| Fluticasone | Inhalation by mouth | 1 June 2017 |
| Fluticasone with Salmeterol | Inhalation by mouth | 1 June 2017 |
| Follitropin Alfa | Injection | 1 August 2016 |
| Fosinopril with Hydrochlorothiazide | Oral | 1 August 2007 |
| Frusemide | Oral | 1 April 2012 |
| Galantamine | Oral | 1 August 2010 |
| Ganciclovir | Injection | 1 April 2018 |
| Gefitinib | Oral | 1 October 2020 |
| Gemcitabine | Injection | 1 April 2009 |
| Gemfibrozil | Oral | 1 April 2008 |
| Glucose | Injection | 1 August 2009 |
| Hydromorphone | Injection | 1 August 2019 |
| Hydroxocobalamin | Injection | 1 December 2010 |
| Hydroxycarbamide | Oral | 1 October 2020 |
| Hydroxychloroquine | Oral | 1 August 2012 |
| Hyoscine | Injection | 1 December 2017 |
| Icatibant | Oral | 1 October 2020 |
| Ibuprofen | Oral | 1 October 2017 |
| Idarubicin | Injection | 1 April 2011 |
| Imatinib | Oral | 1 October 2016 |
| Imiquimod | Application | 1 December 2012 |
| Indapamide | Oral | 1 August 2012 |
| Infliximab | Injection | 1 December 2015 |
| Insulin glargine | Injection | 1 October 2019 |
| Interferon Beta-1b | Injection | 1 April 2013 |
| Irbesartan | Oral | 1 April 2013 |
| Irbesartan with Hydrochlorothiazide | Oral | 1 April 2013 |
| Isotretinoin | Oral | 1 April 2011 |
| Itraconazole | Oral | 1 December 2016 |
| Ivabradine | Oral | 1 October 2018 |
| Lamivudine | Oral | 1 August 2012 |
| Lamivudine with Zidovudine (Applied to the lamivudine component) | Oral | 1 August 2012 |
| Lamivudine with Zidovudine (Applied to the zidovudine component) | Oral | 1 August 2013 |
| Latanoprost | Application to the eye | 1 August 2012 |
| Latanoprost with Timolol | Application to the eye | 1 August 2012 |
| Leflunomide | Oral | 1 August 2011 |
| Lercanidipine | Oral | 1 August 2007 |
| Letrozole | Oral | 1 April 2012 |
| Levodopa with carbidopa | Oral | 1 April 2020 |
| Levodopa with carbidopa and entacapone | Oral | 1 August 2020 |
| Levonorgestrel with Ethinylestradiol | Oral | 1 April 2013 |
| Lincomycin | Injection | 1 June 2018 |
| Loperamide | Oral | 1 December 2012 |
| Losartan | Oral | 1 April 2013 |
| Lurasidone | Oral | 1 August 2020 |
| Macrogol 3350 | Oral | 1 December 2010 |
| Meloxicam | Oral | 1 August 2007 |
| Memantine | Oral | 1 April 2010 |
| Mercaptopurine | Oral | 1 December 2020 |
| Methylprednisolone | Injection | 1 August 2011 |
| Metoclopramide | Oral | 1 April 2014 |
| Metoprolol succinate | Oral | 1 August 2014 |
| Metronidazole | Injection | 1 April 2008 |
| Misoprostol | Oral | 1 August 2013 |
| Modafinil | Oral | 1 April 2016 |
| Mometasone | Application | 1 April 2013 |
| Montelukast | Oral | 1 August 2013 |
| Morphine | Injection | 1 August 2016 |
| Morphine | Oral | 1 August 2009 |
| Moxonidine | Oral | 1 June 2018 |
| Mycophenolic Acid | Oral | 1 April 2012 |
| Naloxone | Injection | 1 April 2017 |
| Naltrexone | Oral | 1 December 2007 |
| Nebivolol | Oral | 1 August 2018 |
| Nevirapine | Oral | 1 December 2012 |
| Nicorandil | Oral | 1 April 2015 |
| Nifedipine | Oral | 1 August 2007 |
| Nitofurantoin | Oral | 1 August 2020 |
| Nortriptyline | Oral | 1 August 2017 |
| Octreotide | Injection | 1 December 2007 |
| Olanzapine | Oral | 1 April 2012 |
| Olmesartan | Oral | 1 April 2013 |
| Olmesartan with Hydrochlorothiazide (Applied to Olmesartan component)* (Applied to the the Hydrochlorothiazide component)** |
Oral | 1 April 2013* 1 December 2016** |
| Olmesartan with Amlodipine (Applied to Olmersartan component ) | Oral | 1 April 2013 |
| Olmesartan with Amlodipine and Hydrochlorothiazide | Oral | 1 April 2020 |
| Omalizumab | Injection | 1 August 2014 |
| Omeprazole and Clarithromycin and Amoxycillin | Oral | 1 December 2010 |
| Oxazepam | Oral | 1 August 2010 |
| Oxybutynin | Oral | 1 August 2007 |
| Oxycodone | Oral | 1 December 2014 |
| Pegfilgrastim | Injection | 1 April 2017 |
| Perindopril with Indapamide | Oral | 1 August 2007 |
| Pioglitazone | Oral | 1 April 2011 |
| Posaconazole | Oral | 1 December 2020 |
| Pramipexole | Oral | 1 August 2012 |
| Prazosin | Oral | 1 April 2012 |
| Pregabalin | Oral | 1 August 2017 |
| Prochlorperazine | Oral | 1 August 2010 |
| Propranolol | Oral | 1 August 2015 |
| Quetiapine | Oral | 1 April 2012 |
| Rasagiline | Oral | 1 Feb 2019 |
| Raloxifene | Oral | 1 December 2014 |
| Riluzole | Oral | 1 December 2012 |
| Risedronate Sodium | Oral | 1 April 2011 |
| Risedronate Sodium and Calcium Carbonate | Oral | 1 April 2011 |
| Risedronate Sodium and Calcium Carbonate with Colecalciferol | Oral | 1 April 2011 |
| Risperidone | Oral | 1 December 2008 |
| Rituximab | Injection | 1 October 2019 |
| Rivastigmine | Transdermal | 1 December 2016 |
| Rizatriptan | Oral | 1 December 2015 |
| Rosuvastatin | Oral | 1 April 2012 |
| Salbutamol | Inhalation | 1 April 2008 |
| Salbutamol | Inhalation by mouth | 1 August 2011 |
| Sevelamer | Oral | 1 December 2019 |
| Sildenafil | Oral | 1 August 2014 |
| Sodium Chloride | Injection | 1 August 2009 |
| Sodium Lactate Compound | Injection | 1 August 2009 |
| Somatropin | Injection | 1 December 2015 |
| Sorbitol with Sodium Citrate and Sodium Lauryl Sulfoacetate | Rectal | 1 August 2010 |
| Tacrolimus | Oral | 1 December 2010 |
| Tadalafil | Oral | 1 October 2020 |
| Telmisartan | Oral | 1 April 2013 |
| Telmisartan with Amlodipine (Applied to Telmarsartan component) | Oral | 1 April 2013 |
| Telmisartan with Hydrochlorothiazide (Applied to Telmisartan component) | Oral | 1 April 2013 |
| Telmisartan with Hydrochlorothiazide (Applied to hydrochlorothiazide component) | Oral | 1 August 2013 |
| Temazepam | Oral | 1 August 2009 |
| Temozolomide | Oral | 1 December 2011 |
| Tenofovir | Oral | 1 August 2017 |
| Tenofovir with emtricitabine | Oral | 1 August 2017 |
| Tenofovir with emtricitabine and efavirenz | Oral | 1 August 2019 |
| Teriflunomide | Oral | 1 June 2019 |
| Tiotropium | Inhalation by mouth | 1 February 2020 |
| Tirofiban | Injection | 1 August 2014 |
| Tobramycin | Injection | 1 August 2016 |
| Tocilizumab | Injection | 1 December 2018 |
| Topotecan | Injection | 1 August 2012 |
| Tranexamic acid | Oral | 1 May 2017 |
| Trastuzumab | Injection | 1 August 2019 |
| Ursodeoxycholic acid | Oral | 1 April 2015 |
| Valganciclovir | Oral | 1 August 2017 |
| Valproic Acid | Oral | 1 August 2007 |
| Valsartan | Oral | 1 April 2013 |
| Valsartan with Hydrochlorothiazide (Valsartan component)* (Hydrochlorothiazide component)** |
Oral | 1 April 2013* 1 December 2014** |
| Vancomycin | Injection | 1 December 2007 |
| Venlafaxine | Oral | 1 April 2012 |
| Voriconazole | Oral | 1 February 2016 |
| Ziprasidone | Oral | 1 December 2013 |
| Zoledronic Acid | Injection | 1 December 2015 |
| Zonisamide | Oral | 1 June 2017 |
2. Administrative 12.5% reductions
| Drug | Manner of Administration | Date of Effect |
|---|---|---|
| Aciclovir | Oral | 1 August 2006 |
| Amitriptyline | Oral | 1 August 2006 |
| Amoxycillin | Oral | 1 August 2006 |
| Amoxycillin with Clavulanic Acid | Oral | 1 August 2006 |
| Bisacodyl | Oral | 1 December 2005 |
| Bupropion | Oral | 1 April 2006 |
| Calcitriol | Oral | 1 August 2005 |
| Calcium Folinate | Injection | 1 April 2006 |
| Captopril | Oral | 1 August 2006 |
| Carboplatin | Injection | 1 December 2006 |
| Cefaclor | Oral | 1 August 2006 |
| Cefotaxime | Injection | 1 December 2006 |
| Ceftriaxone | Injection | 1 December 2006 |
| Cefuroxime | Oral | 1 August 2006 |
| Cephalexin | Oral | 1 August 2006 |
| Cimetidine | Oral | 1 August 2006 |
| Ciprofloxacin | Oral | 1 April 2006 |
| Cisplatin | Injection | 1 August 2006 |
| Citalopram | Oral | 1 August 2005 |
| Clarithromycin | Oral | 1 December 2005 |
| Codeine with Paracetamol | Oral | 1 August 2005 |
| Cromoglycic Acid | Application to the eye | 1 August 2006 |
| Dexamphetamine | Oral | 1 December 2005 |
| Docetaxel | Injection | 1 August 2005 |
| Dolasetron | Injection | 1 April 2006 |
| Dolasetron | Oral | 1 April 2006 |
| Doxorubicin | Injection/Intravesical | 1 August 2005 |
| Electrolyte Replacement (Oral) | Oral | 1 December 2005 |
| Enalapril | Oral | 1 August 2006 |
| Erythromycin | Oral | 1 December 2005 |
| Escitalopram | Oral | 1 August 2005 |
| Esomeprazole | Oral | 1 April 2006 |
| Etidronic Acid and Calcium | Oral | 1 August 2005 |
| Etoposide | Injection | 1 December 2005 |
| Famciclovir | Oral | 1 August 2006 |
| Famotidine | Oral | 1 August 2006 |
| Fluconazole | Oral | 1 December 2006 |
| Fluorouracil | Injection | 1 August 2006 |
| Fluoxetine | Oral | 1 August 2005 |
| Fluvastatin | Oral | 1 August 2005 |
| Fluvoxamine | Oral | 1 August 2005 |
| Fosinopril | Oral | 1 August 2006 |
| Frusemide | Injection | 1 December 2005 |
| Gabapentin | Oral | 1 August 2005 |
| Gliclazide | Oral | 1 April 2006 |
| Glimepiride | Oral | 1 April 2006 |
| Granisetron | Oral | 1 April 2006 |
| Granisetron | Injection | 1 April 2006 |
| Imipramine | Oral | 1 August 2006 |
| Ipratropium | Inhalation | 1 August 2005 |
| Irinotecan | Injection | 1 December 2006 |
| Lansoprazole | Oral | 1 April 2006 |
| Lamotrigine | Oral | 1 August 2005 |
| Levetiracetam | Oral | 1 August 2005 |
| Lisinopril | Oral | 1 August 2006 |
| Metformin | Oral | 1 December 2005 |
| Methotrexate | Injection | 1 December 2005 |
| Methylphenidate | Oral | 1 December 2005 |
| Mirtazapine | Oral | 1 August 2005 |
| Mitozantrone | Injection | 1 April 2006 |
| Moclobemide | Oral | 1 August 2005 |
| Naratriptan | Oral | 1 April 2007 |
| Nizatidine | Oral | 1 August 2006 |
| Omeprazole | Oral | 1 April 2006 |
| Ondansetron | Injection | 1 April 2006 |
| Ondansetron | Oral | 1 April 2006 |
| Oxaliplatin | Injection | 1 December 2006 |
| Oxcarbazepine | Oral | 1 August 2005 |
| Paclitaxel | Injection | 1 August 2005 |
| Pantoprazole | Oral | 1 April 2006 |
| Paracetamol | Oral | 1 December 2005 |
| Paroxetine | Oral | 1 August 2005 |
| Pemetrexed | Injection | 1 August 2005 |
| Perindopril | Oral | 1 August 2006 |
| Pravastatin | Oral | 1 August 2005 |
| Quinapril | Oral | 1 August 2006 |
| Rabeprazole | Oral | 1 April 2006 |
| Ramipril | Oral | 1 August 2006 |
| Ranitidine | Oral | 1 August 2006 |
| Reboxetine | Oral | 1 August 2005 |
| Roxithromycin | Oral | 1 December 2005 |
| Sertraline | Oral | 1 August 2005 |
| Simvastatin | Oral | 1 August 2005 |
| Sumatriptan | Oral | 1 April 2007 |
| Terbinafine | Oral | 1 December 2005 |
| Tiagabine | Oral | 1 August 2005 |
| Topiramate | Oral | 1 August 2005 |
| Tramadol | Injection | 1 August 2005 |
| Tramadol | Oral | 1 August 2005 |
| Trandolapril | Oral | 1 August 2006 |
| Tropisetron | Injection | 1 April 2006 |
| Tropisetron | Oral | 1 April 2006 |
| Valaciclovir | Oral | 1 August 2006 |
| Vigabatrin | Oral | 1 August 2005 |
| Vinorelbine | Injection | 1 August 2005 |
| Zolmitriptan | Oral | 1 April 2007 |
3. Partial 12.5% reductions
| Drug | Manner of Administration | Details of Partial Reduction | Date of Effect |
|---|---|---|---|
| Doxorubicin, Pegylated Liposomal | Injection | 3.5% (to account for use in ovarian cancer and Kaposi’s sarcoma) | 1 August 2005 |
| Ezetimibe with Simvastatin | Oral | Applied to the simvastatin component | 1 August 2005 |
| Metformin with Glibenclamide | Oral | Applied to the metformin component | 1 December 2005 |
| Gemcitabine | Injection | 6.1% to account for use in pancreatic and bladder cancer | 1 August 2005 |
| Rosiglitazone with Metformin | Oral | Applied to the metformin component | 1 December 2005 |
| Quinapril with Hydrochlorothiazide | Oral | Applied to the quinapril component | 1 August 2006 |
| Trandolapril with Verapamil | Oral | Applied to the trandolapril component | 1 August 2006 |
| Alendronic Acid with Colecalciferol | Oral | Applied to alendronic acid component | 1 December 2007 |
| Goserelin Acetate and Bicalutamide | Implantation/Oral | Applied to bicalutamide component | 1 August 2008 |
