Drugs and manners of administration that meet the 42 month clock
Page last updated: 27 October 2023
This page lists the drugs and manners of administration (MoA) that will meet the 42 month clock for the 2024 April Cycle. A drug/MoA will meet the 42 month clock if the brand’s pharmaceutical item has been on F2 for at least 42 months, and at least 30 months have passed since the first price disclosure price reduction for any brand of the same drug/MoA.
Brands of a drug/MoA which have met the 42 month clock will satisfy the ‘designated brand’ criteria under s99ADHC(1)(a) of the National Health Act 1953 (the Act). Under s99ADH(1)(c) of the Act, designated brands with an AEMP of more than $4 will be subject to a 30% Unadjusted Price Reduction (UPR), OR a 10% UPR, if there has been discounting averaging at least 12.5% over the last 3 data collection periods including the one for which calculations are performed and there has not been a price reduction under s99ADH of the Act.
Drug/MoAs that have not met the 42 month clock may satisfy criteria for a future cycle. Updates will be published in April and October of each year.
Further information on the 42 month clock as well as the application of the 30% threshold is available in the Price Disclosure Guidelines.
Drugs and manners of administration that meet the 42 month clock for the 2024 April Cycle:
|
Legal Instrument Drug |
Legal Instrument MoA |
Meets 42 month clock |
|---|---|---|
|
Abacavir with lamivudine |
Oral |
Yes |
|
Acamprosate |
Oral |
Yes |
|
Acarbose |
Oral |
Yes |
|
Aciclovir |
Oral |
Yes |
|
Acitretin |
Oral |
Yes |
|
Adefovir |
Oral |
Yes |
|
Alendronic acid |
Oral |
Yes |
|
Alendronic acid with colecalciferol |
Oral |
Yes |
|
Alendronic acid with colecalciferol and calcium |
Oral |
Yes |
|
Allopurinol |
Oral |
Yes |
|
Alprazolam |
Oral |
Yes |
|
Amiodarone |
Oral |
Yes |
|
Amisulpride |
Oral |
Yes |
|
Amlodipine |
Oral |
Yes |
|
Amlodipine with atorvastatin |
Oral |
Yes |
|
Amlodipine with valsartan |
Oral |
Yes |
|
Amlodipine with valsartan and hydrochlorothiazide |
Oral |
Yes |
|
Amoxicillin |
Oral |
Yes |
|
Amoxicillin with clavulanic acid |
Oral |
Yes |
|
Ampicillin |
Injection |
Yes |
|
Anastrozole |
Oral |
Yes |
|
Aripiprazole |
Oral |
Yes |
|
Atazanavir |
Oral |
Yes |
|
Atenolol |
Oral |
Yes |
|
Atomoxetine |
Oral |
Yes |
|
Atorvastatin |
Oral |
Yes |
|
Azacitidine |
Injection |
Yes |
|
Azathioprine |
Oral |
Yes |
|
Azithromycin |
Oral |
Yes |
|
Baclofen |
Oral |
Yes |
|
Baclofen |
Injection |
Yes |
|
Bicalutamide |
Oral |
Yes |
|
Bisacodyl |
Oral |
Yes |
|
Bisoprolol |
Oral |
Yes |
|
Bivalirudin |
Injection |
Yes |
|
Bleomycin |
Injection |
Yes |
|
Bosentan |
Oral |
Yes |
|
Calcitriol |
Oral |
Yes |
|
Candesartan |
Oral |
Yes |
|
Candesartan with hydrochlorothiazide |
Oral |
Yes |
|
Capecitabine |
Oral |
Yes |
|
Captopril |
Oral |
Yes |
|
Carboplatin |
Injection |
Yes |
|
Carvedilol |
Oral |
Yes |
|
Cefaclor |
Oral |
Yes |
|
Cefalexin |
Oral |
Yes |
|
Cefazolin |
Injection |
Yes |
|
Cefepime |
Injection |
Yes |
|
Cefotaxime |
Injection |
Yes |
|
Ceftriaxone |
Injection |
Yes |
|
Celecoxib |
Oral |
Yes |
|
Ciclosporin |
Oral |
Yes |
|
Ciprofloxacin |
Oral |
Yes |
|
Cisplatin |
Injection |
Yes |
|
Citalopram |
Oral |
Yes |
|
Clarithromycin |
Oral |
Yes |
|
Clindamycin |
Oral |
Yes |
|
Clomipramine |
Oral |
Yes |
|
Clopidogrel |
Oral |
Yes |
|
Clopidogrel with aspirin |
Oral |
Yes |
|
Clozapine |
Oral |
Yes |
|
Codeine with paracetamol |
Oral |
Yes |
|
Cyproterone |
Oral |
Yes |
|
Desferrioxamine |
Injection |
Yes |
|
Desvenlafaxine |
Oral |
Yes |
|
Dexamethasone |
Injection |
Yes |
|
Diazepam |
Oral |
Yes |
|
Diclofenac |
Oral |
Yes |
|
Diltiazem |
Oral |
Yes |
|
Docetaxel |
Injection |
Yes |
|
Donepezil |
Oral |
Yes |
|
Dorzolamide |
Application to the eye |
Yes |
|
Dorzolamide with timolol |
Application to the eye |
Yes |
|
Dosulepin |
Oral |
Yes |
|
Doxorubicin |
Injection/intravesical |
Yes |
|
Doxorubicin - pegylated liposomal |
Injection |
Yes |
|
Doxycycline |
Oral |
Yes |
|
Duloxetine |
Oral |
Yes |
|
Eplerenone |
Oral |
Yes |
|
Electrolyte replacement, oral |
Oral |
Yes |
|
Enalapril |
Oral |
Yes |
|
Enalapril with hydrochlorothiazide |
Oral |
Yes |
|
Entecavir |
Oral |
Yes |
|
Epirubicin |
Injection/intravesical |
Yes |
|
Epoprostenol |
Injection |
Yes |
|
Escitalopram |
Oral |
Yes |
|
Esomeprazole |
Oral |
Yes |
|
Etoposide |
Injection |
Yes |
|
Exemestane |
Oral |
Yes |
|
Ezetimibe |
Oral |
Yes |
|
Ezetimibe with simvastatin |
Oral |
Yes |
|
Famciclovir |
Oral |
Yes |
|
Famotidine |
Oral |
Yes |
|
Felodipine |
Oral |
Yes |
|
Fenofibrate |
Oral |
Yes |
|
Fentanyl |
Transdermal |
Yes |
|
Filgrastim |
Injection |
Yes |
|
Flucloxacillin |
Injection |
Yes |
|
Fluconazole |
Injection |
Yes |
|
Fluconazole |
Oral |
Yes |
|
Fludarabine |
Injection |
Yes |
|
Fluorouracil |
Injection |
Yes |
|
Fluoxetine |
Oral |
Yes |
|
Flutamide |
Oral |
Yes |
|
Fluvoxamine |
Oral |
Yes |
|
Folinic acid |
Injection |
Yes |
|
Fosinopril |
Oral |
Yes |
|
Fosinopril with hydrochlorothiazide |
Oral |
Yes |
|
Furosemide |
Injection |
Yes |
|
Furosemide |
Oral |
Yes |
|
Gabapentin |
Oral |
Yes |
|
Galantamine |
Oral |
Yes |
|
Ganciclovir |
Injection |
Yes |
|
Gemcitabine |
Injection |
Yes |
|
Gemfibrozil |
Oral |
Yes |
|
Glimepiride |
Oral |
Yes |
|
Glyceryl trinitrate |
Transdermal |
Yes |
|
Granisetron |
Injection |
Yes |
|
Granisetron |
Oral |
Yes |
|
Hydrocortisone |
Oral |
Yes |
|
Hydrocortisone |
Rectal |
Yes |
|
Hydroxocobalamin |
Injection |
Yes |
|
Hydroxychloroquine |
Oral |
Yes |
|
Hyoscine |
Injection |
Yes |
|
Idarubicin |
Injection |
Yes |
|
Imatinib |
Oral |
Yes |
|
Imiquimod |
Application |
Yes |
|
Indapamide |
Oral |
Yes |
|
Infliximab |
Injection |
Yes |
|
Ipratropium |
Inhalation |
Yes |
|
Irbesartan |
Oral |
Yes |
|
Irbesartan with hydrochlorothiazide |
Oral |
Yes |
|
Irinotecan |
Injection |
Yes |
|
Iron polymaltose complex |
Injection |
Yes |
|
Isosorbide mononitrate |
Oral |
Yes |
|
Isotretinoin |
Oral |
Yes |
|
Itraconazole |
Oral |
Yes |
|
Ivabradine |
Oral |
Yes |
|
Labetalol |
Oral |
Yes |
|
Lamivudine |
Oral |
Yes |
|
Lamivudine with zidovudine |
Oral |
Yes |
|
Lamotrigine |
Oral |
Yes |
|
Lansoprazole |
Oral |
Yes |
|
Latanoprost |
Application to the eye |
Yes |
|
Latanoprost with timolol |
Application to the eye |
Yes |
|
Leflunomide |
Oral |
Yes |
|
Lercanidipine |
Oral |
Yes |
|
Letrozole |
Oral |
Yes |
|
Levetiracetam |
Oral |
Yes |
|
Levonorgestrel with ethinylestradiol |
Oral |
Yes |
|
Lincomycin |
Injection |
Yes |
|
Lisinopril |
Oral |
Yes |
|
Macrogol 3350 |
Oral |
Yes |
|
Meloxicam |
Oral |
Yes |
|
Memantine |
Oral |
Yes |
|
Metformin |
Oral |
Yes |
|
Methotrexate |
Injection |
Yes |
|
Methylprednisolone |
Injection |
Yes |
|
Metoclopramide |
Oral |
Yes |
|
Metoprolol |
Oral |
Yes |
|
Metoprolol succinate |
Oral |
Yes |
|
Mirtazapine |
Oral |
Yes |
|
Mitozantrone |
Injection |
Yes |
|
Moclobemide |
Oral |
Yes |
|
Modafinil |
Oral |
Yes |
|
Mometasone |
Application |
Yes |
|
Montelukast |
Oral |
Yes |
|
Moxonidine |
Oral |
Yes |
|
Mycophenolic acid |
Oral |
Yes |
|
Naloxone |
Injection |
Yes |
|
Nevirapine |
Oral |
Yes |
|
Nicorandil |
Oral |
Yes |
|
Nifedipine |
Oral |
Yes |
|
Nitrazepam |
Oral |
Yes |
|
Norfloxacin |
Oral |
Yes |
|
Olanzapine |
Oral |
Yes |
|
Olmesartan |
Oral |
Yes |
|
Olmesartan with hydrochlorothiazide |
Oral |
Yes |
|
Omeprazole |
Oral |
Yes |
|
Ondansetron |
Oral |
Yes |
|
Oxaliplatin |
Injection |
Yes |
|
Oxybutynin |
Oral |
Yes |
|
Oxycodone |
Oral |
Yes |
|
Paclitaxel |
Injection |
Yes |
|
Pamidronic acid |
Injection |
Yes |
|
Pantoprazole |
Oral |
Yes |
|
Paroxetine |
Oral |
Yes |
|
Pegfilgrastim |
Injection |
Yes |
|
Pemetrexed |
Injection |
Yes |
|
Perindopril |
Oral |
Yes |
|
Perindopril with amlodipine |
Oral |
Yes |
|
Perindopril with indapamide |
Oral |
Yes |
|
Pindolol |
Oral |
Yes |
|
Pioglitazone |
Oral |
Yes |
|
Pramipexole |
Oral |
Yes |
|
Pravastatin |
Oral |
Yes |
|
Prazosin |
Oral |
Yes |
|
Pregabalin |
Oral |
Yes |
|
Prochlorperazine |
Oral |
Yes |
|
Quetiapine |
Oral |
Yes |
|
Quinapril |
Oral |
Yes |
|
Rabeprazole |
Oral |
Yes |
|
Raloxifene |
Oral |
Yes |
|
Ramipril |
Oral |
Yes |
|
Ranitidine |
Oral |
Yes |
|
Riluzole |
Oral |
Yes |
|
Risedronic acid |
Oral |
Yes |
|
Risedronic acid and calcium |
Oral |
Yes |
|
Risperidone |
Oral |
Yes |
|
Rituximab |
Injection |
Yes |
|
Rizatriptan |
Oral |
Yes |
|
Rosuvastatin |
Oral |
Yes |
|
Roxithromycin |
Oral |
Yes |
|
Salbutamol |
Inhalation |
Yes |
|
Sertraline |
Oral |
Yes |
|
Sildenafil |
Oral |
Yes |
|
Simvastatin |
Oral |
Yes |
|
Sorbitol with sodium citrate dihydrate and sodium lauryl sulfoacetate |
Rectal |
Yes |
|
Sotalol |
Oral |
Yes |
|
Sumatriptan |
Oral |
Yes |
|
Tacrolimus |
Oral |
Yes |
|
Tamoxifen |
Oral |
Yes |
|
Telmisartan |
Oral |
Yes |
|
Telmisartan with amlodipine |
Oral |
Yes |
|
Telmisartan with hydrochlorothiazide |
Oral |
Yes |
|
Temazepam |
Oral |
Yes |
|
Temozolomide |
Oral |
Yes |
|
Tenofovir with emtricitabine |
Oral |
Yes |
|
Tenofovir |
Oral |
Yes |
|
Terbinafine |
Oral |
Yes |
|
Teriflunomide |
Oral |
Yes |
|
Tirofiban |
Injection |
Yes |
|
Tobramycin |
Injection |
Yes |
|
Tobramycin |
Inhalation |
Yes |
|
Topiramate |
Oral |
Yes |
|
Topotecan |
Injection |
Yes |
|
Tramadol |
Injection |
Yes |
|
Tramadol |
Oral |
Yes |
|
Trandolapril |
Oral |
Yes |
|
Tranexamic acid |
Oral |
Yes |
|
Trastuzumab |
Injection |
Yes |
|
Trimethoprim with sulfamethoxazole |
Oral |
Yes |
|
Tropisetron |
Injection |
Yes |
|
Ursodeoxycholic acid |
Oral |
Yes |
|
Valaciclovir |
Oral |
Yes |
|
Valganciclovir |
Oral |
Yes |
|
Valproic acid |
Oral |
Yes |
|
Valsartan |
Oral |
Yes |
|
Valsartan with hydrochlorothiazide |
Oral |
Yes |
|
Vancomycin |
Injection |
Yes |
|
Venlafaxine |
Oral |
Yes |
|
Vincristine |
Injection |
Yes |
|
Vinorelbine |
Injection |
Yes |
|
Voriconazole |
Oral |
Yes |
|
Ziprasidone |
Oral |
Yes |
|
Zoledronic acid |
Injection |
Yes |
|
Zolmitriptan |
Oral |
Yes |
