Severe behavioural disturbances
Clinical criteria:
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Patient must have autism spectrum disorder,
AND
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The treatment must be under the supervision of a paediatrician or psychiatrist,
AND
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The treatment must be in combination with non-pharmacological measures.
Population criteria:
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Patient must be under 18 years of age.
Behaviour disturbances are defined as severe aggression and injuries to self or others where non-pharmacological methods alone have been unsuccessful.
The diagnosis of autism spectrum disorder must be made based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) or ICD-10 international classification of mental and behavioural disorders.