Severe pain

Clinical criteria:

• Patient must have had or would have inadequate pain management with maximum tolerated doses of non-opioid and other opioid analgesics; OR

• Patient must be unable to use non-opioid and other opioid analgesics due to contraindications or intolerance; OR

• The treatment must be part of pre-operative care; OR

• The treatment must be used as an analgesic adjunct in general anaesthesia.