0008	Pregnancy must be excluded prior to administration of this drug.
0017	The risk of drug dependence is high.
0018	Neutropenia and agranulocytosis are more frequent in the elderly, especially in the early months of therapy.
0068	Severe cholestatic hepatitis has been reported with this drug. Significant risk factors are age, particularly greater than 55 years, and duration of treatment longer than 14 days.
0075	This drug is an irreversible monoamine oxidase inhibitor.
0078	Prochlorperazine may be associated with parkinsonism and tardive dyskinesia and should be used for short-term treatment only.
0097	Treatment with interferon alfa has been associated with depression and suicide in some patients. Patients with a history of suicidal ideation or depressive illness should be warned of the risks. Psychiatric status during therapy should be monitored.
0099	Abuse of clonazepam has been reported. Refer to the current product information.
0104	Careful monitoring of patients is mandatory.
0110	There are reports of fatal hepatotoxicity, particularly in children. There is increasing evidence of dose-related teratogenesis from this drug.
0121	Buprenorphine with naloxone soluble film and buprenorphine with naloxone sublingual tablet do not meet all the criteria for bioequivalence. Patients being switched between sublingual tablets and soluble films may therefore require a dosage adjustment.
0123	Pharmaceutical benefits containing gemcitabine may have different concentrations.
7776	Careful monitoring of patients is mandatory.
8211	The risk of drug dependence is high.
8286	Use of ACE inhibitors during pregnancy is contraindicated since these drugs have been associated with foetal death in utero.
8299	The myocardial depressant effects of verapamil hydrochloride and of beta-blocking drugs are additive.
8357	Treatment with peginterferon alfa has been associated with depression and suicide in some patients. Patients with a history of suicidal ideation or depressive illness should be warned of the risks. Psychiatric status during therapy should be monitored.
8358	Ribavirin is a category X drug and must not be given to pregnant women. Pregnancy in female patients or in the partners of male patients must be avoided during treatment and during the 6 months period after cessation of treatment.
9216	Monitor for post-injection syndrome for at least two hours after each injection.
9409	Teriflunomide is a category X drug and must not be given to pregnant women or women of childbearing potential who are not currently using reliable contraception. Pregnancy should be avoided for two years after cessation of therapy, unless special wash-out procedures are carried out. 
9950	Selective serotonin (5HT1) agonists are contraindicated in patients with known or suspected coronary artery disease. The drug should not be used within 24 hours of ergotamine or dihydroergotamine use.
11011	This is a category X drug and must not be given to pregnant women. Pregnancy must be avoided during treatment and for at least 3 months following cessation of therapy.
13054	In placebo controlled trials in elderly patients with dementia there was a significantly higher incidence of cerebrovascular adverse events, such as stroke (including fatalaties) and transient ischaemic attacks, in patients treated with risperidone compared with patients treated with placebo.
13100	This drug is a potent teratogen - pregnancy should be avoided for at least two years after cessation of therapy.
13939	This drug should not be used during pregnancy as it may result in feminisation of the male foetus.
14061	EpiPen and Anapen products have different administration techniques and should not be prescribed to the same patient without training in their use.
14151	Visual field defects have been reported with this drug.
14170	Severe cholestatic hepatitis has been reported with this drug. Significant risk factors are age, particularly greater than 55 years, and duration of treatment longer than 14 days.
14180	Serum electrolytes should be checked regularly
14417	Flecainide acetate should be avoided in patients with poor cardiac function.
14441	There are concerns about the incidence of benign intracranial hypertension associated with this drug.
14463	This drug is an irreversible monoamine oxidase inhibitor.
14511	This drug causes birth defects. 
14512	This drug has been reported to cause other frequent and potentially serious toxicity.
14688	Leflunomide is a category X drug and must not be given to pregnant women. Pregnancy should be avoided for two years after cessation of therapy, unless special wash-out procedures are carried out.
14697	Severe thrombocytopenia has been reported with this drug.
14764	Desmopressin nasal spray may be associated with an increased risk of hyponatraemia compared to the oral formulations.
14779	Treatment with interferon alfa has been associated with depression and suicide in some patients. Patients with a history of suicidal ideation or depressive illness should be warned of the risks. Psychiatric status during therapy should be monitored.
14876	Episodes of sudden onset of sleep without warning, during activity, have been reported with this drug.
15136	Naltrexone hydrochloride is contraindicated in patients receiving opioid drugs.
15277	Contraindications to treatment include known sensitivity to botulinum toxin.
15467	Care should be taken when treating patients with advanced age and significant cognitive impairment with dopamine agonists.
15534	Thalidomide is a category X drug and must not be given to pregnant women. Pregnancy in female patients or in the partners of male patients must be avoided during treatment and for 1 month after cessation of treatment.
15898	Progressive multifocal leukoencephalopathy has been reported with this drug.
16366	Hepatotoxicity has been reported with this drug.
16637	The myocardial depressant effects of this drug and of beta-blocking drugs are additive.
16638	Serum electrolytes should be checked regularly.
16671	Appropriate contraceptive measures should be taken by women of child-bearing age in whom spironolactone therapy has been initiated.
16673	Prochlorperazine may be associated with parkinsonism and tardive dyskinesia and should be used for short-term treatment only.
16674	Sulfonylureas may cause hypoglycaemia, particularly in the elderly.
16723	Serum sickness-like reactions have been reported with this drug, especially in children.
16737	Nitrofurantoin may cause peripheral neuritis and severe pulmonary reactions.
16741	Regular blood and urine checks are essential.
16745	There is an increased risk of severe adverse reactions with this combination in the elderly.
16840	This drug is a category X drug and must not be given to pregnant women. Pregnancy in female patients or in the partners of male patients must be avoided during treatment and for 1 month after cessation of treatment.
16865	Because of variable effects of food on absorption of sustained release theophylline preparations, patients stabilised on one brand should not be changed to another without appropriate monitoring.
18192	 The listed brands have NOT been shown to be bioequivalent and should not be interchanged.
