Price Disclosure Reductions for 2014 October Cycle

(First cycle under Simplified Price Disclosure amendments)

The price disclosure outcomes for this cycle were calculated in accordance with the National Health Act 1953 (the Act) and National Health (Pharmaceutical Benefits) Regulations 1960 (the Regulations) as amended for Simplified Price Disclosure.

To assist readers to understand the 2014 October Cycle Outcomes Summary, the diagram sets out the processes and sample inputs for the regular cycle with a 1 October 2014 reduction day. It shows the two types of price differences that are important under the Simplified Price Disclosure amendments (see blue/ vertical and red/ diagonal arrows - further explanation below). The PBS Price is the base price before mark-ups and fees. A PDF version of the Diagram (146 KB) is also available.

Processes and sample inputs for the regular cycle with a 1 October 2014 reduction day

In the Outcomes Summary below:

MoA = manner of administration of a form of drug

Average AEMP = the weighted average approved ex-manufacturer price (PBS price) for brands of the pharmaceutical item during the data collection period ending 31 March 2014.  Average AEMP is calculated in accordance with Regulation 37J (Step 3) of the calculation method in the Regulations. *

WAPD (drug/MoA) = the weighted average percentage difference between the Average AEMPs and the prices disclosed by companies across all brands of a drug and manner of administration (drug/MoA). This is the blue/vertical arrow in the diagram above.  WAPD is calculated in accordance with Regulation 37R (Step 10) of the Regulations. *

WADP (pharmaceutical item) = the weighted average disclosed price, which is worked out by reducing the Average AEMP for a brand by its WAPD. See Regulation 37S (Step 11) of the Regulations.  This is the amount determined in the price disclosure legal determination for each brand of pharmaceutical item. For medicines that meet the 10% test, this amount is also determined as the adjusted approved ex-manufacturer price, which will become the new base PBS price, before fees and mark-ups, on 1 October 2014 (unless there is an intervening lower price). *

April AEMP = the approved ex-manufacturer price effective on 1 April 2014 for the pricing quantity for brands of the relevant pharmaceutical item.  The April 2014 price may be different to the Average AEMP during the data collection period, for example, due to a 1 April 2014 price disclosure reduction or PBPA price increase, or to a price change during the data collection period. 

April to October 2014 Price Difference = the percentage difference between:

  • the 1 April 2014 approved ex-manufacturer price for brands of each pharmaceutical item; and
  • the proposed 1 October 2014 new base PBS price. This price is equivalent to the WADP (i.e.: Average AEMP minus WAPD). The actual 1 October 2014 base PBS price may change if there are changes in prices or listings before then (e.g.: lower price / pricing quantity changes).

The April to October price difference is the red/ diagonal arrow in the diagram above.  This percentage difference is the one used for the 10% test under subsection 99ADH(1)(c) of the Act.*  Only medicines with at least a 10% difference between the price on the relevant day (1 April 2014 in this case)  and the WADP meet the 10% test for a 1 October 2014 reduction.  All the medicines in the Outcome Summary below meet the 10% test for reduction.

The April to October percentage difference may be different across different pharmaceutical items of the same drug/MoA because of, for example:

  • rounding when applying the WAPD to different pharmaceutical item prices; or
  • different price increases on the relevant day (1 April) for different pharmaceutical items; or
  • differences in the weighting of the different Average AEMPs for different items because of a price change or item listing at different times in the cycle. 

*Further explanation of the concepts above, and the calculation for price disclosure, is included in the explanation of the price disclosure method and sample price disclosure calculation on the Price Disclosure (SPD) web page.

Legal Determination & Next Steps

The weighted average disclosed prices for each brand, including brands with no reduction, are in the legal determination on the ComLaw website. Price disclosure reductions will apply to brands listed in Schedule 1 of the legal determination. Those in Schedule 2 of the determination will not take a price disclosure reduction because the percentage difference between their April PBS approved ex-manufacturer price and the weighted average disclosed price was below 10%.  A new brand listed after 31 March 2014 for a pharmaceutical item that has an existing brand with a determination in Schedule 1 of the determination will also take the reduction on 1 October 2014 under section 99ADHA of the Act.

Final prices applicable on 1 October 2014 (including price to pharmacy, Dispensed Price Maximum Quantity and price premiums) will be available under a ‘Confirmation of New Prices Resulting from Price Disclosure Cycles’ link on this web page from early September 2014. To further assist companies and other stakeholders indicative 1 October 2014 prices (including price to pharmacy, Dispensed Price Maximum Quantity and price premiums) will be published by mid-July 2014, after completion of further pricing calculations. Subscribe to PBS News to receive notice when they become available.

An agreed process for responsible persons to raise any questions or concerns arising from an outcome mentioned above is set out in the Price Disclosure Dispute Resolution Administrative Process. The date for lodgement of disputes is 5 pm AEST on Thursday, 26 June 2014

Note: The documents on this page may not be accessible. If you need assistance please email the Price Disclosure team or call 02 6289 2303.

2014 October Cycle Outcomes Summary

This summary only covers medicines taking a reduction.  The price disclosure legal determination mentioned above includes brands with no reductions.

NOTE: The prices below do not include fees and mark-ups. Indicative new 1 October 2014 prices, with fees and mark-ups, will be published by mid-July 2014.

Outcomes for brands of pharmaceutical items containing filgrastim for injection in the 2014 October Cycle have been amended. Data was resubmitted for these brands following consideration of matters raised by a responsible person.

2014 October Cycle Outcomes Summary
2014 October Cycle Outcomes Summary
Legal Instrument Drug Legal Instrument MoA Legal Instrument Form Average AEMP ($) WAPD
(%)
across a drug/MoA
WADP
potential
October 14
PBS Price (AEMP)
($)
per pharmaceutical item
April 14
AEMP
($)
Percentage difference between April 14 and October 14  PBS prices (AEMP)
(%)
per pharmaceutical item
[Average AEMP minus WAPD =
WADP]
[Difference between April AEMP & WADP =
% Difference]
Aciclovir Oral Tablet 200 mg 16.05 35.35% 10.38 11.97 13.28%
Aciclovir Oral Tablet 800 mg 69.90 35.35% 45.19 52.11 13.28%
Alendronic acid Oral Tablet 40 mg (as alendronate sodium) 38.41 43.22% 21.81 27.65 21.12%
Alendronic acid Oral Tablet 70 mg (as alendronate sodium) 11.63 43.22% 6.60 8.37 21.15%
Allopurinol Oral Tablet 100 mg 2.14 14.10% 1.84 2.14 14.02%
Allopurinol Oral Tablet 300 mg 2.52 14.10% 2.16 2.52 14.29%
Alprazolam Oral Tablet 1 mg 4.89 12.63% 4.27 4.89 12.68%
Alprazolam Oral Tablet 2 mg 7.58 12.63% 6.62 7.58 12.66%
Alprazolam Oral Tablet 250 micrograms 1.74 12.63% 1.52 1.74 12.64%
Alprazolam Oral Tablet 500 micrograms 2.81 12.63% 2.46 2.81 12.46%
Amisulpride Oral Tablet 100 mg 17.33 32.23% 11.74 13.36 12.13%
Amisulpride Oral Tablet 200 mg 74.64 32.23% 50.58 57.53 12.08%
Amisulpride Oral Tablet 400 mg 135.35 32.23% 91.73 104.33 12.08%
Amlodipine Oral Tablet 10 mg (as besylate) 4.28 40.69% 2.54 2.94 13.61%
Amlodipine Oral Tablet 5 mg (as besylate) 2.44 40.69% 1.45 1.68 13.69%
Ampicillin Injection Powder for injection 1 g (as sodium) 5.88 11.04% 5.23 5.88 11.05%
Ampicillin Injection Powder for injection 500 mg (as sodium) 3.58 11.04% 3.18 3.58 11.17%
Anastrozole Oral Tablet 1 mg 110.72 30.91% 76.50 91.69 16.57%
Atorvastatin Oral Tablet 10 mg (as calcium) 14.89 66.23% 5.03 9.30 45.91%
Atorvastatin Oral Tablet 20 mg (as calcium) 21.98 66.23% 7.42 13.72 45.92%
Atorvastatin Oral Tablet 40 mg (as calcium) 30.94 66.23% 10.45 19.32 45.91%
Atorvastatin Oral Tablet 80 mg (as calcium) 44.23 66.23% 14.94 27.62 45.91%
Azathioprine Oral Tablet 25 mg 18.09 13.01% 15.74 18.09 12.99%
Azathioprine Oral Tablet 50 mg 30.80 13.01% 26.79 30.80 13.02%
Azithromycin Oral Tablet 500 mg (as dihydrate) 11.87 49.50% 5.99 7.68 22.01%
Azithromycin Oral Tablet 600 mg (as dihydrate) 61.68 49.50% 31.15 36.89 15.56%
Baclofen Oral Tablet 10 mg 12.15 14.59% 10.38 12.15 14.57%
Baclofen Oral Tablet 25 mg 26.56 14.59% 22.68 26.56 14.61%
Bicalutamide Oral Tablet 50 mg 122.79 22.66% 94.97 105.62 10.08%
Bisoprolol Oral Tablet containing bisoprolol fumarate 10 mg 44.24 41.53% 25.87 32.87 21.30%
Bisoprolol Oral Tablet containing bisoprolol fumarate 2.5 mg 28.32 41.53% 16.56 21.04 21.29%
Bisoprolol Oral Tablet containing bisoprolol fumarate 5 mg 35.39 41.53% 20.69 26.29 21.30%
Calcitriol Oral Capsule 0.25 microgram 22.27 13.33% 19.30 22.27 13.34%
Candesartan Oral Tablet containing candesartan cilexetil 16 mg 15.28 17.92% 12.54 15.28 17.93%
Candesartan Oral Tablet containing candesartan cilexetil 32 mg 18.47 17.92% 15.16 18.47 17.92%
Candesartan Oral Tablet containing candesartan cilexetil 4 mg 1.71 17.92% 1.40 1.71 18.13%
Candesartan Oral Tablet containing candesartan cilexetil 8 mg 5.11 17.92% 4.19 5.11 18.00%
Candesartan with hydrochlorothiazide Oral Tablet containing candesartan cilexetil 16 mg with hydrochlorothiazide 12.5 mg 16.79 22.58% 13.00 16.79 22.57%
Candesartan with hydrochlorothiazide Oral Tablet containing candesartan cilexetil 32 mg with hydrochlorothiazide 12.5 mg 19.98 22.58% 15.47 19.98 22.57%
Candesartan with hydrochlorothiazide Oral Tablet containing candesartan cilexetil 32 mg with hydrochlorothiazide 25 mg 21.49 22.58% 16.64 21.49 22.57%
Captopril Oral Tablet 12.5 mg 5.02 14.36% 4.30 5.02 14.34%
Captopril Oral Tablet 25 mg 7.26 14.36% 6.22 7.26 14.33%
Captopril Oral Tablet 50 mg 14.33 14.36% 12.27 14.33 14.38%
Carboplatin Injection Solution for I.V. injection 150 mg in 15 mL 15.48 13.24% 13.43 15.48 13.24%
Carboplatin Injection Solution for I.V. injection 450 mg in 45 mL 29.16 13.24% 25.30 29.16 13.24%
Carboplatin Injection Solution for I.V. injection 50 mg in 5 mL 6.41 13.24% 5.56 6.41 13.26%
Cefalotin Injection Powder for injection 1 g (as sodium) 13.31 23.67% 10.16 11.35 10.48%
Cefepime Injection Powder for injection 1 g (as hydrochloride) 8.74 47.85% 4.56 6.95 34.39%
Cefepime Injection Powder for injection 2 g (as hydrochloride) 16.65 47.85% 8.68 13.25 34.49%
Cefotaxime Injection Powder for injection 1 g (as sodium) 1.33 10.38% 1.19 1.33 10.53%
Cefotaxime Injection Powder for injection 2 g (as sodium) 2.45 10.38% 2.20 2.45 10.20%
Ceftriaxone Injection Powder for injection 1 g (as sodium) 2.41 43.61% 1.36 1.55 12.26%
Ceftriaxone Injection Powder for injection 2 g (as sodium) 4.47 43.61% 2.52 2.87 12.20%
Ceftriaxone Injection Powder for injection 500 mg (as sodium) 1.54 43.61% 0.87 0.99 12.12%
Cephazolin Injection Powder for injection 1 g (as sodium) 7.93 56.57% 3.44 4.15 17.11%
Cephazolin Injection Powder for injection 2 g (as sodium) 3.64 56.57% 1.58 1.90 16.84%
Cephazolin Injection Powder for injection 500 mg (as sodium) 5.96 56.57% 2.59 3.12 16.99%
Ciprofloxacin Oral Tablet 250 mg (as hydrochloride) 6.54 32.57% 4.41 5.12 13.87%
Ciprofloxacin Oral Tablet 500 mg (as hydrochloride) 12.79 32.57% 8.62 10.01 13.89%
Ciprofloxacin Oral Tablet 750 mg (as hydrochloride) 19.28 32.57% 13.00 15.09 13.85%
Citalopram Oral Tablet 10 mg (as hydrobromide) 2.35 43.75% 1.32 1.60 17.50%
Citalopram Oral Tablet 20 mg (as hydrobromide) 3.56 43.75% 2.00 2.43 17.70%
Citalopram Oral Tablet 40 mg (as hydrobromide) 6.03 43.75% 3.39 4.11 17.52%
Clarithromycin Oral Powder for oral liquid 250 mg per 5 mL, 50 mL 14.98 15.59% 12.64 14.98 15.62%
Clarithromycin Oral Tablet 250 mg 3.32 15.59% 2.80 3.32 15.66%
Clarithromycin Oral Tablet 500 mg 47.30 15.59% 39.93 47.30 15.58%
Clopidogrel Oral Tablet 75 mg 20.47 50.34% 10.17 11.52 11.72%
Clopidogrel Oral Tablet 75 mg (as besilate) 20.47 50.34% 10.17 11.52 11.72%
Clopidogrel Oral Tablet 75 mg (as hydrogen sulfate) 20.47 50.34% 10.17 11.52 11.72%
Clozapine Oral Tablet 100 mg 167.20 27.52% 121.19 140.83 13.95%
Clozapine Oral Tablet 200 mg 334.41 27.52% 242.38 281.67 13.95%
Clozapine Oral Tablet 25 mg 44.59 27.52% 32.32 37.56 13.95%
Clozapine Oral Tablet 50 mg 89.18 27.52% 64.64 75.12 13.95%
Desferrioxamine Injection Powder for injection containing desferrioxamine mesylate 2 g 32.40 11.30% 28.74 32.40 11.30%
Desferrioxamine Injection Powder for injection containing desferrioxamine mesylate 500 mg 81.02 11.30% 71.86 81.02 11.31%
Dexamethasone Injection Injection containing dexamethasone sodium phosphate equivalent to 4 mg dexamethasone phosphate in 1 mL 7.26 24.34% 5.49 6.77 18.91%
Dexamethasone Injection Injection containing dexamethasone sodium phosphate equivalent to 8 mg dexamethasone phosphate in 2 mL 13.19 24.34% 9.98 12.30 18.86%
Donepezil Oral Tablet containing donepezil hydrochloride 10 mg 63.50 58.13% 26.59 63.50 58.13%
Donepezil Oral Tablet containing donepezil hydrochloride 5 mg 63.50 58.13% 26.59 63.50 58.13%
Doxorubicin Injection/intravesical Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 10 mg in 5 mL single dose vial 4.61 39.07% 2.81 3.72 24.46%
Doxorubicin Injection/intravesical Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 100 mg in 50 mL single dose vial 38.97 39.07% 23.74 31.41 24.42%
Doxorubicin Injection/intravesical Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 200 mg in 100 mL single dose vial 77.94 39.07% 47.49 62.82 24.40%
Doxorubicin Injection/intravesical Solution for I.V. injection or intravesical administration containing doxorubicin hydrochloride 50 mg in 25 mL single dose vial 19.49 39.07% 11.88 15.71 24.38%
Duloxetine Oral Capsule 30 mg (as hydrochloride) 21.60 35.83% 13.86 21.60 35.83%
Duloxetine Oral Capsule 60 mg (as hydrochloride) 30.86 35.83% 19.80 30.86 35.84%
Etoposide Injection Powder for I.V. infusion 1 g (as phosphate) 174.62 13.39% 151.24 174.62 13.39%
Etoposide Injection Powder for I.V. infusion 100 mg (as phosphate) 17.47 13.39% 15.13 17.47 13.39%
Etoposide Injection Solution for I.V. infusion 100 mg in 5 mL vial 87.33 13.39% 75.64 87.33 13.39%
Famciclovir Oral Tablet 125 mg 106.07 48.06% 55.09 65.13 15.42%
Famciclovir Oral Tablet 250 mg 106.08 48.06% 55.10 65.13 15.40%
Famciclovir Oral Tablet 500 mg 159.11 48.06% 82.64 97.69 15.41%
Famotidine Oral Tablet 20 mg 4.83 15.72% 4.07 4.83 15.73%
Famotidine Oral Tablet 40 mg 4.83 15.72% 4.07 4.83 15.73%
Filgrastim Injection Injection 120 micrograms in 0.2 mL single use pre-filled syringe (Nivestim) 503.11 15.20% 426.64 503.11 15.20%
Filgrastim Injection Injection 300 micrograms in 0.5 mL single use pre-filled syringe (Neupogen) 1,257.77 15.20% 1,066.59 1,257.77 15.20%
Filgrastim Injection Injection 300 micrograms in 0.5 mL single use pre-filled syringe (Nivestim) 1,257.77 15.20% 1,066.59 1,257.77 15.20%
Filgrastim Injection Injection 300 micrograms in 0.5 mL single use pre-filled syringe (TevaGrastim) 1,257.77 15.20% 1,066.59 1,257.77 15.20%
Filgrastim Injection Injection 300 micrograms in 0.5 mL single use pre-filled syringe (Zarzio) 628.88 15.20% 533.29 628.88 15.20%
Filgrastim Injection Injection 300 micrograms in 1 mL 1,257.77 15.20% 1,066.59 1,257.77 15.20%
Filgrastim Injection Injection 480 micrograms in 0.5 mL single use pre-filled syringe (Neupogen) 2,016.29 15.20% 1,709.81 2,016.29 15.20%
Filgrastim Injection Injection 480 micrograms in 0.5 mL single use pre-filled syringe (Nivestim) 2,016.29 15.20% 1,709.81 2,016.29 15.20%
Filgrastim Injection Injection 480 micrograms in 0.5 mL single use pre-filled syringe (Zarzio) 1,008.14 15.20% 854.90 1,008.14 15.20%
Filgrastim Injection Injection 480 micrograms in 0.8 mL single use pre-filled syringe (TevaGrastim) 2,016.29 15.20% 1,709.81 2,016.29 15.20%
Filgrastim Injection Injection 480 micrograms in 1.6 mL 2,016.29 15.20% 1,709.81 2,016.29 15.20%
Flucloxacillin Injection Powder for injection 1 g (as sodium) 6.25 33.35% 4.17 6.25 33.28%
Flucloxacillin Injection Powder for injection 500 mg (as sodium) 3.99 33.35% 2.66 3.99 33.33%
Fluconazole Injection Solution for I.V. infusion 100 mg in 50 mL 10.26 82.26% 1.82 4.81 62.16%
Fluconazole Injection Solution for I.V. infusion 200 mg in 100 mL 19.32 82.26% 3.43 9.06 62.14%
Fluconazole Injection Solution for I.V. infusion 400 mg in 200 mL 30.40 82.26% 5.39 14.25 62.18%
Fluconazole Oral Capsule 100 mg 43.28 29.59% 30.47 35.47 14.10%
Fluconazole Oral Capsule 200 mg 84.30 29.59% 59.36 69.09 14.08%
Fluconazole Oral Capsule 50 mg 22.22 29.59% 15.65 18.21 14.06%
Fludarabine Injection Powder for I.V. injection containing fludarabine phosphate 50 mg 103.11 54.94% 46.46 53.87 13.76%
Fludarabine Injection Solution for I.V. injection 50 mg fludarabine phosphate in 2 mL 515.60 54.94% 232.33 269.40 13.76%
Fluorouracil Injection Injection 1000 mg in 20 mL 5.45 11.38% 4.83 5.45 11.38%
Fluorouracil Injection Injection 2500 mg in 50 mL 13.62 11.38% 12.07 13.62 11.38%
Fluorouracil Injection Injection 500 mg in 10 mL 16.02 11.38% 14.20 16.02 11.36%
Fluorouracil Injection Injection 5000 mg in 100 mL 27.22 11.38% 24.12 27.22 11.39%
Fluoxetine Oral Capsule 20 mg (as hydrochloride) 7.34 28.95% 5.22 5.81 10.15%
Fluoxetine Oral Tablet, dispersible, 20 mg (as hydrochloride) 7.34 28.95% 5.22 5.81 10.15%
Folinic acid Injection Injection containing calcium folinate equivalent to 100 mg folinic acid in 10 mL 8.38 43.14% 4.76 5.49 13.30%
Folinic acid Injection Injection containing calcium folinate equivalent to 1000 mg folinic acid in 100 mL 83.72 43.14% 47.60 54.85 13.22%
Folinic acid Injection Injection containing calcium folinate equivalent to 300 mg folinic acid in 30 mL 24.49 43.14% 13.93 16.05 13.21%
Folinic acid Injection Injection containing calcium folinate equivalent to 50 mg folinic acid in 5 mL 9.07 43.14% 5.16 5.94 13.13%
Frusemide Injection Injection 20 mg in 2 mL 2.59 41.22% 1.52 2.33 34.76%
Galantamine Oral Capsule (prolonged release) 16 mg (as hydrobromide) 49.06 24.27% 37.15 42.41 12.40%
Galantamine Oral Capsule (prolonged release) 24 mg (as hydrobromide) 58.46 24.27% 44.27 50.54 12.41%
Galantamine Oral Capsule (prolonged release) 8 mg (as hydrobromide) 40.10 24.27% 30.37 34.67 12.40%
Gemcitabine Injection Powder for I.V. infusion 1 g (as hydrochloride) 37.35 55.32% 16.69 24.27 31.23%
Gemcitabine Injection Powder for I.V. infusion 2 g (as hydrochloride) 74.87 55.32% 33.45 48.66 31.26%
Gemcitabine Injection Powder for I.V. infusion 200 mg (as hydrochloride) 7.56 55.32% 3.38 4.91 31.16%
Gemcitabine Injection Solution concentrate for I.V. infusion 1 g (as hydrochloride) in 25 mL 37.35 55.32% 16.69 24.27 31.23%
Gemcitabine Injection Solution concentrate for I.V. infusion 1000 mg (as hydrochloride) in 100 mL 37.35 55.32% 16.69 24.27 31.23%
Gemcitabine Injection Solution concentrate for I.V. infusion 2 g (as hydrochloride) in 50 mL 74.87 55.32% 33.45 48.66 31.26%
Gemcitabine Injection Solution concentrate for I.V. infusion 200 mg (as hydrochloride) in 20 mL 7.56 55.32% 3.38 4.91 31.16%
Gemcitabine Injection Solution concentrate for I.V. infusion 200 mg (as hydrochloride) in 5 mL 7.56 55.32% 3.38 4.91 31.16%
Gemcitabine Injection Solution concentrate for I.V. infusion 500 mg (as hydrochloride) in 50 mL 18.68 55.32% 8.35 12.14 31.22%
Gemcitabine Injection Solution for injection 1 g (as hydrochloride) in 26.3 mL 37.35 55.32% 16.69 24.27 31.23%
Gemcitabine Injection Solution for injection 2 g (as hydrochloride) in 52.6 mL 74.87 55.32% 33.45 48.66 31.26%
Gemcitabine Injection Solution for injection 200 mg (as hydrochloride) in 5.3 mL 7.56 55.32% 3.38 4.91 31.16%
Glimepiride Oral Tablet 1 mg 1.32 13.19% 1.15 1.32 12.88%
Glimepiride Oral Tablet 2 mg 2.53 13.19% 2.20 2.53 13.04%
Glimepiride Oral Tablet 3 mg 3.23 13.19% 2.80 3.23 13.31%
Glimepiride Oral Tablet 4 mg 3.96 13.19% 3.44 3.96 13.13%
Glyceryl trinitrate Transdermal Transdermal patch 120 mg 22.15 10.72% 19.78 22.15 10.70%
Glyceryl trinitrate Transdermal Transdermal patch 18 mg 16.90 10.72% 15.09 16.90 10.71%
Glyceryl trinitrate Transdermal Transdermal patch 25 mg 16.90 10.72% 15.09 16.90 10.71%
Glyceryl trinitrate Transdermal Transdermal patch 36 mg 22.15 10.72% 19.78 22.15 10.70%
Glyceryl trinitrate Transdermal Transdermal patch 40 mg 16.90 10.72% 15.09 16.90 10.71%
Glyceryl trinitrate Transdermal Transdermal patch 50 mg 22.15 10.72% 19.78 22.15 10.70%
Glyceryl trinitrate Transdermal Transdermal patch 54 mg 22.15 10.72% 19.78 22.15 10.70%
Glyceryl trinitrate Transdermal Transdermal patch 80 mg 22.15 10.72% 19.78 22.15 10.70%
Granisetron Injection Concentrated injection 3 mg (as hydrochloride) in 3 mL 10.09 60.58% 3.98 5.56 28.42%
Idarubicin Injection Solution for I.V. injection containing idarubicin hydrochloride 10 mg in 10 mL 272.32 45.45% 148.55 272.32 45.45%
Idarubicin Injection Solution for I.V. injection containing idarubicin hydrochloride 5 mg in 5 mL 140.84 45.45% 76.83 140.84 45.45%
Irbesartan Oral Tablet 150 mg 7.80 39.06% 4.75 7.80 39.10%
Irbesartan Oral Tablet 300 mg 15.58 39.06% 9.49 15.58 39.09%
Irbesartan Oral Tablet 75 mg 5.46 39.06% 3.33 5.46 39.01%
Irbesartan with hydrochlorothiazide Oral Tablet 150 mg-12.5 mg 9.31 38.06% 5.77 9.31 38.02%
Irbesartan with hydrochlorothiazide Oral Tablet 300 mg-12.5 mg 17.09 38.06% 10.59 17.09 38.03%
Irbesartan with hydrochlorothiazide Oral Tablet 300 mg-25 mg 18.61 38.06% 11.53 18.61 38.04%
Irinotecan Injection I.V. injection containing irinotecan hydrochloride trihydrate 100 mg in 5 mL 27.60 50.85% 13.57 22.00 38.32%
Irinotecan Injection I.V. injection containing irinotecan hydrochloride trihydrate 300 mg in 15 mL 82.73 50.85% 40.66 65.95 38.35%
Irinotecan Injection I.V. injection containing irinotecan hydrochloride trihydrate 40 mg in 2 mL 11.04 50.85% 5.43 8.80 38.30%
Irinotecan Injection I.V. injection containing irinotecan hydrochloride trihydrate 500 mg in 25 mL 141.44 50.85% 69.52 112.76 38.35%
Iron polymaltose complex Injection Injection 100 mg (iron) in 2 mL 26.00 21.88% 20.31 26.00 21.88%
Isotretinoin Oral Capsule 10 mg 43.32 21.47% 34.02 38.44 11.50%
Isotretinoin Oral Capsule 20 mg 67.52 21.47% 53.02 59.91 11.50%
Isotretinoin Oral Capsule 40 mg 60.94 21.47% 47.86 54.07 11.49%
Lamivudine Oral Oral solution 10 mg per mL, 240 mL 86.48 35.27% 55.98 72.86 23.17%
Lamivudine Oral Oral solution 5 mg per mL, 240 mL 69.91 35.27% 45.25 58.90 23.17%
Lamivudine Oral Tablet 100 mg 125.47 35.27% 81.22 105.71 23.17%
Lamivudine Oral Tablet 150 mg 236.89 35.27% 153.34 199.58 23.17%
Lamivudine Oral Tablet 300 mg 236.89 35.27% 153.34 199.58 23.17%
Lamivudine with zidovudine Oral Tablet 150 mg-300 mg 484.17 18.68% 393.73 484.17 18.68%
Letrozole Oral Tablet 2.5 mg 111.71 35.85% 71.66 94.16 23.90%
Meloxicam Oral Capsule 15 mg 9.95 35.81% 6.39 7.22 11.50%
Meloxicam Oral Capsule 7.5 mg 6.82 35.81% 4.38 4.95 11.52%
Meloxicam Oral Tablet 15 mg 9.95 35.81% 6.39 7.22 11.50%
Meloxicam Oral Tablet 7.5 mg 6.82 35.81% 4.38 4.95 11.52%
Metoprolol Oral Tablet containing metoprolol tartrate 100 mg 3.13 10.12% 2.81 3.13 10.22%
Metoprolol Oral Tablet containing metoprolol tartrate 50 mg 2.45 10.12% 2.20 2.45 10.20%
Metronidazole Injection I.V. infusion 500 mg in 100 mL 2.18 53.60% 1.01 1.20 15.83%
Mirtazapine Oral Tablet 15 mg 5.96 37.64% 3.72 4.32 13.89%
Mirtazapine Oral Tablet 15 mg (orally disintegrating) 10.29 37.64% 6.42 7.46 13.94%
Mirtazapine Oral Tablet 30 mg 8.95 37.64% 5.58 6.49 14.02%
Mirtazapine Oral Tablet 30 mg (orally disintegrating) 13.72 37.64% 8.56 9.94 13.88%
Mirtazapine Oral Tablet 45 mg 14.93 37.64% 9.31 10.82 13.96%
Mirtazapine Oral Tablet 45 mg (orally disintegrating) 20.68 37.64% 12.90 14.98 13.89%
Montelukast Oral Tablet, chewable, 4 mg (as sodium) 28.91 29.33% 20.43 28.91 29.33%
Montelukast Oral Tablet, chewable, 5 mg (as sodium) 27.18 29.33% 19.21 27.18 29.32%
Mycophenolic acid Oral Capsule containing mycophenolate mofetil 250 mg 70.07 35.30% 45.34 58.48 22.47%
Mycophenolic acid Oral Tablet (enteric coated) containing mycophenolate sodium equivalent to 180 mg mycophenolic acid 168.18 35.30% 108.81 140.36 22.48%
Mycophenolic acid Oral Tablet (enteric coated) containing mycophenolate sodium equivalent to 360 mg mycophenolic acid 336.34 35.30% 217.61 280.71 22.48%
Mycophenolic acid Oral Tablet containing mycophenolate mofetil 500 mg 140.14 35.30% 90.67 116.96 22.48%
Nitrazepam Oral Tablet 5 mg 1.38 7.30% 1.28 1.50 14.67%
Norfloxacin Oral Tablet 400 mg 4.94 24.27% 3.74 4.22 11.37%
Olanzapine Oral Tablet 10 mg 109.41 56.42% 47.68 73.69 35.30%
Olanzapine Oral Tablet 10 mg (as benzoate) 109.41 56.42% 47.68 73.69 35.30%
Olanzapine Oral Tablet 10 mg (orally disintegrating) 109.41 56.42% 47.68 73.69 35.30%
Olanzapine Oral Tablet 15 mg (orally disintegrating) 164.12 56.42% 71.52 110.53 35.29%
Olanzapine Oral Tablet 2.5 mg 27.35 56.42% 11.92 18.42 35.29%
Olanzapine Oral Tablet 2.5 mg (as benzoate) 27.35 56.42% 11.92 18.42 35.29%
Olanzapine Oral Tablet 20 mg (orally disintegrating) 218.81 56.42% 95.36 147.37 35.29%
Olanzapine Oral Tablet 5 mg 54.15 56.42% 23.60 36.47 35.29%
Olanzapine Oral Tablet 5 mg (as benzoate) 54.15 56.42% 23.60 36.47 35.29%
Olanzapine Oral Tablet 5 mg (orally disintegrating) 54.15 56.42% 23.60 36.47 35.29%
Olanzapine Oral Tablet 7.5 mg 82.07 56.42% 35.77 55.27 35.28%
Olanzapine Oral Tablet 7.5 mg (as benzoate) 82.07 56.42% 35.77 55.27 35.28%
Olanzapine Oral Wafer 10 mg 109.41 56.42% 47.68 73.69 35.30%
Olanzapine Oral Wafer 15 mg 164.12 56.42% 71.52 110.53 35.29%
Olanzapine Oral Wafer 20 mg 218.81 56.42% 95.36 147.37 35.29%
Olanzapine Oral Wafer 5 mg 54.15 56.42% 23.60 36.47 35.29%
Ondansetron Injection I.V. injection 4 mg (as hydrochloride dihydrate) in 2 mL 1.93 53.16% 0.90 1.12 19.64%
Ondansetron Injection I.V. injection 8 mg (as hydrochloride dihydrate) in 4 mL 3.06 53.16% 1.43 1.78 19.66%
Ondansetron Oral Tablet (orally disintegrating) 4 mg 16.17 49.13% 8.23 9.32 11.70%
Ondansetron Oral Tablet (orally disintegrating) 8 mg 25.33 49.13% 12.89 14.59 11.65%
Ondansetron Oral Tablet 4 mg (as hydrochloride dihydrate) 16.17 49.13% 8.23 9.32 11.70%
Ondansetron Oral Tablet 8 mg (as hydrochloride dihydrate) 25.33 49.13% 12.89 14.59 11.65%
Ondansetron Oral Wafer 4 mg 16.17 49.13% 8.23 9.32 11.70%
Ondansetron Oral Wafer 8 mg 25.33 49.13% 12.89 14.59 11.65%
Oxaliplatin Injection Powder for I.V. infusion 100 mg 79.14 76.33% 18.73 31.74 40.99%
Oxaliplatin Injection Powder for I.V. infusion 50 mg 40.97 76.33% 9.70 16.43 40.96%
Oxaliplatin Injection Solution concentrate for I.V. infusion 100 mg in 20 mL 79.14 76.33% 18.73 31.74 40.99%
Oxaliplatin Injection Solution concentrate for I.V. infusion 200 mg in 40 mL 157.74 76.33% 37.34 63.27 40.98%
Oxaliplatin Injection Solution concentrate for I.V. infusion 50 mg in 10 mL 40.97 76.33% 9.70 16.43 40.96%
Paclitaxel Injection Solution concentrate for I.V. infusion 100 mg in 16.7 mL 34.00 53.80% 15.71 21.81 27.97%
Paclitaxel Injection Solution concentrate for I.V. infusion 150 mg in 25 mL 49.57 53.80% 22.90 31.80 27.99%
Paclitaxel Injection Solution concentrate for I.V. infusion 30 mg in 5 mL 10.25 53.80% 4.74 6.58 27.96%
Paclitaxel Injection Solution concentrate for I.V. infusion 300 mg in 50 mL 103.29 53.80% 47.72 66.27 27.99%
Pamidronic acid Injection Concentrated injection containing disodium pamidronate 15 mg in 5 mL 26.24 23.16% 20.16 22.83 11.70%
Pamidronic acid Injection Concentrated injection containing disodium pamidronate 30 mg in 10 mL 52.48 23.16% 40.33 45.67 11.69%
Pamidronic acid Injection Concentrated injection containing disodium pamidronate 60 mg in 10 mL 104.95 23.16% 80.64 91.33 11.70%
Pamidronic acid Injection Concentrated injection containing disodium pamidronate 90 mg in 10 mL 157.43 23.16% 120.97 137.00 11.70%
Pamidronic acid Injection Injection set containing 1 vial powder for I.V. infusion containing disodium pamidronate 90 mg and 1 ampoule solvent 10 mL 157.43 23.16% 120.97 137.00 11.70%
Pamidronic acid Injection Injection set containing 2 vials powder for I.V. infusion containing disodium pamidronate 30 mg and 2 ampoules solvent 10 mL 104.96 23.16% 80.65 91.34 11.70%
Paroxetine Oral Tablet 20 mg (as hydrochloride) 6.31 27.31% 4.59 5.29 13.23%
Paroxetine Oral Tablet 20 mg (as mesilate) 6.31 27.31% 4.59 5.29 13.23%
Pioglitazone Oral Tablet 15 mg (as hydrochloride) 27.74 35.79% 17.81 20.52 13.21%
Pioglitazone Oral Tablet 30 mg (as hydrochloride) 42.67 35.79% 27.40 31.56 13.18%
Pioglitazone Oral Tablet 45 mg (as hydrochloride) 55.48 35.79% 35.62 41.04 13.21%
Pravastatin Oral Tablet containing pravastatin sodium 10 mg 3.84 37.46% 2.40 2.81 14.59%
Pravastatin Oral Tablet containing pravastatin sodium 20 mg 6.10 37.46% 3.81 4.46 14.57%
Pravastatin Oral Tablet containing pravastatin sodium 40 mg 9.50 37.46% 5.94 6.94 14.41%
Pravastatin Oral Tablet containing pravastatin sodium 80 mg 14.60 37.46% 9.13 10.67 14.43%
Prazosin Oral Tablet 1 mg (as hydrochloride) 4.00 14.14% 3.43 4.00 14.25%
Prazosin Oral Tablet 2 mg (as hydrochloride) 6.37 14.14% 5.47 6.37 14.13%
Prazosin Oral Tablet 5 mg (as hydrochloride) 11.44 14.14% 9.82 11.44 14.16%
Prochlorperazine Oral Tablet containing prochlorperazine maleate 5 mg 1.83 28.44% 1.31 1.47 10.88%
Quetiapine Oral Tablet (modified release) 150 mg (as fumarate) 83.85 38.67% 51.43 67.88 24.23%
Quetiapine Oral Tablet (modified release) 200 mg (as fumarate) 114.25 38.67% 70.07 92.49 24.24%
Quetiapine Oral Tablet (modified release) 300 mg (as fumarate) 167.63 38.67% 102.81 135.71 24.24%
Quetiapine Oral Tablet (modified release) 400 mg (as fumarate) 228.50 38.67% 140.14 184.99 24.24%
Quetiapine Oral Tablet (modified release) 50 mg (as fumarate) 59.26 38.67% 36.34 47.97 24.24%
Quetiapine Oral Tablet 100 mg (as fumarate) 83.85 38.67% 51.43 67.88 24.23%
Quetiapine Oral Tablet 200 mg (as fumarate) 114.25 38.67% 70.07 92.49 24.24%
Quetiapine Oral Tablet 25 mg (as fumarate) 29.63 38.67% 18.17 23.99 24.26%
Quetiapine Oral Tablet 300 mg (as fumarate) 167.63 38.67% 102.81 135.71 24.24%
Rabeprazole Oral Tablet containing rabeprazole sodium 10 mg (enteric coated) 18.26 52.89% 8.60 11.15 22.87%
Rabeprazole Oral Tablet containing rabeprazole sodium 20 mg (enteric coated) 18.26 52.89% 8.60 11.15 22.87%
Ramipril Oral Capsule 1.25 mg 1.98 26.91% 1.45 1.64 11.59%
Ramipril Oral Capsule 10 mg 6.42 26.91% 4.69 5.31 11.68%
Ramipril Oral Capsule 2.5 mg 2.90 26.91% 2.12 2.40 11.67%
Ramipril Oral Capsule 5 mg 3.64 26.91% 2.66 3.01 11.63%
Ramipril Oral Pack containing 7 tablets 2.5 mg, 21 tablets 5 mg and 10 capsules 10 mg 5.96 26.91% 4.36 4.93 11.56%
Ramipril Oral Tablet 1.25 mg 1.98 26.91% 1.45 1.64 11.59%
Ramipril Oral Tablet 10 mg 6.42 26.91% 4.69 5.31 11.68%
Ramipril Oral Tablet 2.5 mg 2.90 26.91% 2.12 2.40 11.67%
Ramipril Oral Tablet 5 mg 3.64 26.91% 2.66 3.01 11.63%
Risedronic acid Oral Tablet (enteric coated) containing risedronate sodium 35 mg 32.06 10.50% 28.69 32.06 10.51%
Risedronic acid Oral Tablet containing risedronate sodium 150 mg 34.74 10.50% 31.09 34.74 10.51%
Risedronic acid Oral Tablet containing risedronate sodium 30 mg 218.91 10.50% 195.92 218.91 10.50%
Risedronic acid Oral Tablet containing risedronate sodium 35 mg 32.06 10.50% 28.69 32.06 10.51%
Risedronic acid Oral Tablet containing risedronate sodium 5 mg 32.06 10.50% 28.69 32.06 10.51%
Risperidone Oral Tablet 0.5 mg 3.28 36.89% 2.07 2.42 14.46%
Risperidone Oral Tablet 0.5 mg (orally disintegrating) 5.51 36.89% 3.48 4.06 14.29%
Risperidone Oral Tablet 1 mg 18.98 36.89% 11.98 14.00 14.43%
Risperidone Oral Tablet 1 mg (orally disintegrating) 11.02 36.89% 6.95 8.13 14.51%
Risperidone Oral Tablet 2 mg 43.42 36.89% 27.40 32.03 14.46%
Risperidone Oral Tablet 2 mg (orally disintegrating) 22.13 36.89% 13.97 16.33 14.45%
Risperidone Oral Tablet 3 mg 66.95 36.89% 42.25 49.39 14.46%
Risperidone Oral Tablet 3 mg (orally disintegrating) 32.89 36.89% 20.76 24.26 14.43%
Risperidone Oral Tablet 4 mg 90.38 36.89% 57.04 66.67 14.44%
Risperidone Oral Tablet 4 mg (orally disintegrating) 43.82 36.89% 27.65 32.33 14.48%
Rosuvastatin Oral Tablet 10 mg (as calcium) 30.48 36.46% 19.37 30.48 36.45%
Rosuvastatin Oral Tablet 20 mg (as calcium) 43.40 36.46% 27.58 43.40 36.45%
Rosuvastatin Oral Tablet 40 mg (as calcium) 61.90 36.46% 39.33 61.90 36.46%
Rosuvastatin Oral Tablet 5 mg (as calcium) 20.77 36.46% 13.20 20.77 36.45%
Roxithromycin Oral Tablet 150 mg 2.16 17.51% 1.78 2.16 17.59%
Roxithromycin Oral Tablet 300 mg 2.16 17.51% 1.78 2.16 17.59%
Sertraline Oral Tablet 100 mg (as hydrochloride) 4.73 41.80% 2.75 3.15 12.70%
Sertraline Oral Tablet 50 mg (as hydrochloride) 4.73 41.80% 2.75 3.15 12.70%
Simvastatin Oral Tablet 10 mg 3.51 49.50% 1.77 2.11 16.11%
Simvastatin Oral Tablet 20 mg 5.06 49.50% 2.56 3.04 15.79%
Simvastatin Oral Tablet 40 mg 7.28 49.50% 3.68 4.37 15.79%
Simvastatin Oral Tablet 5 mg 2.54 49.50% 1.28 1.52 15.79%
Simvastatin Oral Tablet 80 mg 10.46 49.50% 5.28 6.28 15.92%
Sodium lactate compound Injection I.V. infusion containing approximately 131 mmol sodium (as lactate and chloride), 5 mmol potassium (as chloride), 2 mmol calcium (as chloride), 29 mmol bicarbonate (as lactate) and 111 mmol chloride per L, 1 L 1.47 13.72% 1.27 1.47 13.61%
Sodium lactate compound Injection I.V. infusion containing approximately 65 mmol sodium (as lactate and chloride), 2.7 mmol potassium (as chloride), 0.9 mmol calcium (as chloride), 14 mmol bicarbonate (as lactate) and 56 mmol chloride per 500 mL, 500 mL 1.03 13.72% 0.89 1.03 13.59%
Sumatriptan Oral Tablet (fast disintegrating) 50 mg (as succinate) 6.09 36.59% 3.86 4.66 17.17%
Sumatriptan Oral Tablet 50 mg (as succinate) 6.09 36.59% 3.86 4.66 17.17%
Temazepam Oral Tablet 10 mg 0.84 11.22% 0.75 0.84 10.71%
Temozolomide Oral Capsule 100 mg 518.23 26.74% 379.66 455.17 16.59%
Temozolomide Oral Capsule 140 mg 714.69 26.74% 523.58 627.72 16.59%
Temozolomide Oral Capsule 180 mg 865.42 26.74% 634.01 795.30 20.28%
Temozolomide Oral Capsule 20 mg 120.97 26.74% 88.62 106.25 16.59%
Temozolomide Oral Capsule 250 mg 1,231.27 26.74% 902.03 1,081.44 16.59%
Temozolomide Oral Capsule 5 mg 41.15 26.74% 30.15 36.14 16.57%
Topotecan Injection Powder for I.V. infusion 4 mg (as hydrochloride) 330.40 65.21% 114.95 145.77 21.14%
Tropisetron Injection I.V. injection 5 mg (as hydrochloride) in 5 mL 18.50 47.19% 9.77 18.50 47.19%
Venlafaxine Oral Capsule (modified release) 150 mg (as hydrochloride) 25.96 51.74% 12.53 18.61 32.67%
Venlafaxine Oral Capsule (modified release) 37.5 mg (as hydrochloride) 12.06 51.74% 5.82 8.65 32.72%
Venlafaxine Oral Capsule (modified release) 75 mg (as hydrochloride) 21.29 51.74% 10.27 15.26 32.70%