First New Brand Price Reductions

Page last updated: 1 December 2018

Drugs where 12.5%, 16% and 25% reductions applied legislatively, administratively and partially

In accordance with division 3A of Part VII of the National Health Act 1953 a statutory price reduction of 25% is applied to existing PBS-listed products when the first new brand or item that is bioequivalent or biosimilar and has the same manner of administration as an existing brand or item lists on the PBS. This reduction increased from 12.5% to 16% on 1 February 2011, then again from 16% to 25% on 1 October 2018.

Administrative price reductions are applied in particular circumstances, for example, where a lower price offer is made by a sponsor.

Note: Statutory price reductions only occur once and are not applied to drugs that have taken a 12.5%, 16% or 25% administrative price reduction.

Note: New drugs with price reductions are in bold italics.

1. Statutory 12.5%, 16% and 25% Reductions

1. Statutory 12.5%, 16% and 25% Reductions
Drug
(for combination drug – 16% applied to component)
Manner of Administration Date of Effect
for 16% SPR
Abacavir with lamivudine Oral 1 February 2018
Abacavir with Lamivudine (Applied to the lamivudine component) Oral 1 August 2012
Abacavir with Lamivudine and Zidovudine (Applied to the lamivudine component) Oral 1 August 2012
Abatacept Injection 1 April 2017
Acamprosate Oral 1 June 2018
Acarbose Oral 1 June 2016
Acitretin Oral 1 April 2014
Adefovir Oral 1 December 2014
Adrenaline Injection 1 June 2018
Alendronic Acid Oral 1 December 2007
Amisulpride Oral 1 August 2007
Amlodipine Oral 1 August 2007
Amlodipine with Atorvastatin (amlodipine component)*
(atorvastatin component)**
Oral 1 August 2007*
1 April 2012**
Amlodipine with Valsartan Oral 1 December 2012
Amlodipine with Valsartan and hydrochlorothiazide Oral 1 December 2012
Anastrozole Oral 1 April 2012
Apomorphine Injection 1 February 2016
Aripiprazole Oral 1 December 2016
Aspirin Oral 1 August 2012
Atenolol Oral 1 April 2011
Atomoxetine Oral 1 August 2016
Atorvastatin Oral 1 April 2012
Azacitidine Injection 1 June 2016
Azithromycin Oral 1 August 2009
Baclofen Injection 1 April 2016
Bicalutamide Oral 1 August 2008
Bimatoprost Application to the eye 1 October 2017
Bisoprolol Oral 1 August 2009
Bivalirudin Injection 1 December 2016
Bleomycin Injection 1 April 2012
Bosentan Oral 1 August 2017
Budesonide with eformoterol Inhalation by mouth 1 April 2018
Buprenorphine Transdermal 1 June 2018
Cabergoline Oral 1 August 2009
Candesartan Oral 1 April 2013
Candesartan with Hydrochlorothiazide (Applied to Candesartan component) Oral 1 April 2013
Candesartan with Hydrochlorothiazide (Applied to Hydrochlorothiazide component) Oral 1 August 2013
Capecitabine Oral 1 August 2014
Carbomer Application to the eye 1 April 2014
Carvedilol Oral 1 April 2008
Cefepime Injection 1 December 2010
Celecoxib Oral 1 December 2014
Cephalothin/Cefalotin Injection 1 August 2008
Cephazolin Injection 1 December 2010
Certolizumab pegol Injection 1 April 2018
Chorionic gonadotrophin Injection 1 August 2017
Clindamycin Oral 1 December 2014
Clonidine Oral 1 April 2017
Clopidogrel Oral 1 April 2010
Clopidogrel with Aspirin Oral 1 April 2010
Cyproterone Oral 1 August 2012
Desvenlafaxine Oral 1 April 2015
Dexamethasone Injection 1 December 2011
Diazepam Oral 1 August 2008
Dicloxacillin Oral 1 June 2018
Diltiazem Oral 1 August 2007
Dipyridamole with aspirin Oral 1 December 2014
Donepezil Oral 1 April 2013
Dorzolamide Application to the eye 1 April 2015
Dorzolamide with timolol Application to the eye 1 December 2014
Doxorubicin - Pegylated Liposomal Injection 1 April 2014
Duloxetine Oral 1 April 2013
Dutasteride Oral 1 December 2017
Enalapril Maleate with Hydrochlorothiazide Oral 1 April 2008
Enoxaparin Injection 1 June 2018
Entecavir Oral 1 December 2016
Epirubicin Injection/Intravesical 1 April 2011
Eplerenone Oral 1 June 2016
Epoprostenol Injection 1 August 2014
Eprosartan Oral 1 April 2013
Eprosartan with Hydrochlorothiazide (Applied to Eprosartan component) Oral 1 April 2013
Etanercept Injection 1 April 2017
Everolimus Oral 1 June 2018
Exemestane Oral 1 August 2011
Ezetimibe Oral 1 June 2018
Ezetimibe and Rosuvastatin Oral 1 June 2018
Ezetimibe with Simvastatin Oral 1 June 2018
Felodipine Oral 1 August 2007
Fentanyl Transdermal 1 August 2011
Filgrastim Injection 1 April 2011
Flecainide Oral 1 October 2016
Flucloxacillin Oral 1 December 2018
Fluconazole Injection 1 December 2007
Fludarabine Injection 1 December 2008
Fluticasone Inhalation by mouth 1 June 2017
Fluticasone with Salmeterol Inhalation by mouth 1 June 2017
Follitropin Alfa Injection 1 August 2016
Fosinopril with Hydrochlorothiazide Oral 1 August 2007
Frusemide Oral 1 April 2012
Galantamine Oral 1 August 2010
Ganciclovir Injection 1 April 2018
Gemcitabine Injection 1 April 2009
Gemfibrozil Oral 1 April 2008
Glucose Injection 1 August 2009
Hydroxocobalamin Injection 1 December 2010
Hydroxychloroquine Oral 1 August 2012
Hyoscine Injection 1 December 2017
Ibuprofen Oral 1 October 2017
Idarubicin Injection 1 April 2011
Imatinib Oral 1 October 2016
Imiquimod Application 1 December 2012
Indapamide Oral 1 August 2012
Infliximab Injection 1 December 2015
Interferon Beta-1b Injection 1 April 2013
Irbesartan Oral 1 April 2013
Irbesartan with Hydrochlorothiazide Oral 1 April 2013
Isotretinoin Oral 1 April 2011
Itraconazole Oral 1 December 2016
Ivabradine Oral 1 October 2018
Lamivudine Oral 1 August 2012
Lamivudine with Zidovudine (Applied to the lamivudine component) Oral 1 August 2012
Lamivudine with Zidovudine (Applied to the zidovudine component) Oral 1 August 2013
Latanoprost Application to the eye 1 August 2012
Latanoprost with Timolol Application to the eye 1 August 2012
Leflunomide Oral 1 August 2011
Lercanidipine Oral 1 August 2007
Letrozole Oral 1 April 2012
Levonorgestrel with Ethinylestradiol Oral 1 April 2013
Lincomycin Injection 1 June 2018
Loperamide Oral 1 December 2012
Losartan Oral 1 April 2013
Macrogol 3350 Oral 1 December 2010
Meloxicam Oral 1 August 2007
Memantine Oral 1 April 2010
Methylprednisolone Injection 1 August 2011
Metoclopramide Oral 1 April 2014
Metoprolol succinate Oral 1 August 2014
Metronidazole Injection 1 April 2008
Misoprostol Oral 1 August 2013
Modafinil Oral 1 April 2016
Mometasone Application 1 April 2013
Montelukast Oral 1 August 2013
Morphine Injection 1 August 2016
Morphine Oral 1 August 2009
Moxonidine Oral 1 June 2018
Mycophenolic Acid Oral 1 April 2012
Naloxone Injection 1 April 2017
Naltrexone Oral 1 December 2007
Nebivolol Oral 1 August 2018
Nevirapine Oral 1 December 2012
Nicorandil Oral 1 April 2015
Nifedipine Oral 1 August 2007
Nortriptyline Oral 1 August 2017
Octreotide Injection 1 December 2007
Olanzapine Oral 1 April 2012
Olmesartan Oral 1 April 2013
Olmesartan with Hydrochlorothiazide
(Applied to Olmesartan component)*
(Applied to the the Hydrochlorothiazide component)**
Oral
1 April 2013*
1 December 2016**
Olmesartan with Amlodipine (Applied to Olmersartan component ) Oral 1 April 2013
Omalizumab Injection 1 August 2014
Omeprazole and Clarithromycin and Amoxycillin Oral 1 December 2010
Oxazepam Oral 1 August 2010
Oxybutynin Oral 1 August 2007
Oxycodone Oral 1 December 2014
Pegfilgrastim Injection 1 April 2017
Perindopril with Indapamide Oral 1 August 2007
Pioglitazone Oral 1 April 2011
Pramipexole Oral 1 August 2012
Prazosin Oral 1 April 2012
Pregabalin Oral 1 August 2017
Prochlorperazine Oral 1 August 2010
Propranolol Oral 1 August 2015
Quetiapine Oral 1 April 2012
Raloxifene Oral 1 December 2014
Riluzole Oral 1 December 2012
Risedronate Sodium Oral 1 April 2011
Risedronate Sodium and Calcium Carbonate Oral 1 April 2011
Risedronate Sodium and Calcium Carbonate with Colecalciferol Oral 1 April 2011
Risperidone Oral 1 December 2008
Rivastigmine Transdermal 1 December 2016
Rizatriptan Oral 1 December 2015
Rosuvastatin Oral 1 April 2012
Salbutamol Inhalation 1 April 2008
Salbutamol   Inhalation by mouth 1 August 2011
Sildenafil Oral 1 August 2014
Sodium Chloride Injection 1 August 2009
Sodium Lactate Compound Injection 1 August 2009
Somatropin Injection 1 December 2015
Sorbitol with Sodium Citrate and Sodium Lauryl Sulfoacetate Rectal 1 August 2010
Tacrolimus Oral 1 December 2010
Telmisartan Oral 1 April 2013
Telmisartan with Amlodipine (Applied to Telmarsartan component) Oral 1 April 2013
Telmisartan with Hydrochlorothiazide (Applied to Telmisartan component) Oral 1 April 2013
Telmisartan with Hydrochlorothiazide (Applied to hydrochlorothiazide component) Oral 1 August 2013
Temazepam Oral 1 August 2009
Temozolomide Oral 1 December 2011
Tenofovir Oral 1 August 2017
Tenofovir with emtricitabine Oral 1 August 2017
Tirofiban Injection 1 August 2014
Tobramycin Injection 1 August 2016
Tocilizumab Injection 1 December 2018
Topotecan Injection 1 August 2012
Tranexamic acid Oral 1 May 2017
Ursodeoxycholic acid Oral 1 April 2015
Valganciclovir Oral 1 August 2017
Valproic Acid Oral 1 August 2007
Valsartan Oral 1 April 2013
Valsartan with Hydrochlorothiazide (Valsartan component)*
(Hydrochlorothiazide component)**
Oral  1 April 2013*
1 December 2014**
Vancomycin Injection 1 December 2007
Venlafaxine Oral 1 April 2012
Voriconazole Oral 1 February 2016
Ziprasidone Oral 1 December 2013
Zoledronic Acid Injection 1 December 2015
Zonisamide Oral 1 June 2017

2. Administrative 12.5% reductions

2. Administrative 12.5% reductions
Drug Manner of Administration Date of Effect
Aciclovir Oral 1 August 2006
Amitriptyline Oral 1 August 2006
Amoxycillin Oral 1 August 2006
Amoxycillin with Clavulanic Acid Oral 1 August 2006
Bisacodyl Oral 1 December 2005
Bupropion Oral 1 April 2006
Calcitriol Oral 1 August 2005
Calcium Folinate Injection 1 April 2006
Captopril Oral 1 August 2006
Carboplatin Injection 1 December 2006
Cefaclor Oral 1 August 2006
Cefotaxime Injection 1 December 2006
Ceftriaxone Injection 1 December 2006
Cefuroxime Oral 1 August 2006
Cephalexin Oral 1 August 2006
Cimetidine Oral 1 August 2006
Ciprofloxacin Oral 1 April 2006
Cisplatin Injection 1 August 2006
Citalopram Oral 1 August 2005
Clarithromycin Oral 1 December 2005
Codeine with Paracetamol Oral 1 August 2005
Cromoglycic Acid Application to the eye 1 August 2006
Dexamphetamine Oral 1 December 2005
Docetaxel Injection 1 August 2005
Dolasetron Injection 1 April 2006
Dolasetron Oral 1 April 2006
Doxorubicin Injection/Intravesical 1 August 2005
Electrolyte Replacement (Oral) Oral 1 December 2005
Enalapril Oral 1 August 2006
Erythromycin Oral 1 December 2005
Escitalopram Oral 1 August 2005
Esomeprazole Oral 1 April 2006
Etidronic Acid and Calcium Oral 1 August 2005
Etoposide Injection 1 December 2005
Famciclovir Oral 1 August 2006
Famotidine Oral 1 August 2006
Fluconazole Oral 1 December 2006
Fluorouracil Injection 1 August 2006
Fluoxetine Oral 1 August 2005
Fluvastatin Oral 1 August 2005
Fluvoxamine Oral 1 August 2005
Fosinopril Oral 1 August 2006
Frusemide Injection 1 December 2005
Gabapentin Oral 1 August 2005
Gliclazide Oral 1 April 2006
Glimepiride Oral 1 April 2006
Granisetron Oral 1 April 2006
Granisetron Injection 1 April 2006
Imipramine Oral 1 August 2006
Ipratropium Inhalation 1 August 2005
Irinotecan Injection 1 December 2006
Lansoprazole Oral 1 April 2006
Lamotrigine Oral 1 August 2005
Levetiracetam Oral 1 August 2005
Lisinopril Oral 1 August 2006
Metformin Oral 1 December 2005
Methotrexate Injection 1 December 2005
Methylphenidate Oral 1 December 2005
Mirtazapine Oral 1 August 2005
Mitozantrone Injection 1 April 2006
Moclobemide Oral 1 August 2005
Naratriptan Oral 1 April 2007
Nizatidine Oral 1 August 2006
Omeprazole Oral 1 April 2006
Ondansetron Injection 1 April 2006
Ondansetron Oral 1 April 2006
Oxaliplatin Injection 1 December 2006
Oxcarbazepine Oral 1 August 2005
Paclitaxel Injection 1 August 2005
Pantoprazole Oral 1 April 2006
Paracetamol Oral 1 December 2005
Paroxetine Oral 1 August 2005
Pemetrexed Injection 1 August 2005
Perindopril Oral 1 August 2006
Pravastatin Oral 1 August 2005
Quinapril Oral 1 August 2006
Rabeprazole Oral 1 April 2006
Ramipril Oral 1 August 2006
Ranitidine Oral 1 August 2006
Reboxetine Oral 1 August 2005
Roxithromycin Oral 1 December 2005
Sertraline Oral 1 August 2005
Simvastatin Oral 1 August 2005
Sumatriptan Oral 1 April 2007
Terbinafine Oral 1 December 2005
Tiagabine Oral 1 August 2005
Topiramate Oral 1 August 2005
Tramadol Injection 1 August 2005
Tramadol Oral 1 August 2005
Trandolapril Oral 1 August 2006
Tropisetron Injection 1 April 2006
Tropisetron Oral 1 April 2006
Valaciclovir Oral 1 August 2006
Vigabatrin Oral 1 August 2005
Vinorelbine Injection 1 August 2005
Zolmitriptan Oral 1 April 2007

3. Partial 12.5% reductions

3. Partial 12.5% reductions
Drug Manner of Administration Details of Partial Reduction Date of Effect
Doxorubicin, Pegylated Liposomal Injection 3.5% (to account for use in ovarian cancer and Kaposi’s sarcoma) 1 August 2005
Ezetimibe with Simvastatin Oral Applied to the simvastatin component 1 August 2005
Metformin with Glibenclamide Oral Applied to the metformin component 1 December 2005
Gemcitabine Injection 6.1% to account for use in pancreatic and  bladder cancer 1 August 2005
Rosiglitazone with Metformin Oral Applied to the metformin component 1 December 2005
Quinapril with Hydrochlorothiazide Oral Applied to the quinapril component 1 August 2006
Trandolapril with Verapamil Oral Applied to the trandolapril component 1 August 2006
Alendronic Acid with Colecalciferol Oral Applied to alendronic acid component 1 December 2007
Goserelin Acetate and Bicalutamide Implantation/Oral Applied to bicalutamide component 1 August 2008